Differential response of mast cells separated from various organs and basophils of dogs to the fluoroquinolone antimicrobial levofloxacin

Archives of Toxicology

Volumn 75, Issue 4, 2001, Pages 227-233

  Mori, Kazuhiko ^a   Shibano, Mayumi ^a   Satoh, Hiroshi ^a   Takasuna, Kiyoshi ^a   Furuhama, Kazuhisa ^a  

^a DAIICHI SANKYO CO   (Japan)

Author keywords

Canine mast cells; Fluoroquinolone; Heterogeneity; Histamine release

Indexed keywords

ALCIAN BLUE; CALCIMYCIN; CALCIUM IONOPHORE; COMPOUND 48-80; GUANINE NUCLEOTIDE BINDING PROTEIN; HISTAMINE; LEVOFLOXACIN; PERTUSSIS TOXIN; QUINOLINE DERIVED ANTIINFECTIVE AGENT; SAFRAZINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BASOPHIL; BLOOD; CELL HETEROGENEITY; CONNECTIVE TISSUE; CONTROLLED STUDY; DOG; DRUG SENSITIVITY; FEMALE; HISTAMINE RELEASE; HISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; LIVER; LUNG; MALE; MAST CELL; MAST CELL DEGRANULATION; NONHUMAN; PRIORITY JOURNAL; SKIN; STOMACH MUCOSA;

ANIMALS; ANTI-INFECTIVE AGENTS; BASOPHILS; CALCIMYCIN; CONNECTIVE TISSUE; DOGS; FEMALE; GTP-BINDING PROTEINS; HISTAMINE RELEASE; IONOPHORES; L-LACTATE DEHYDROGENASE; LIVER; MALE; MAST CELLS; MUCOUS MEMBRANE; OFLOXACIN; PERTUSSIS TOXIN; SKIN; VIRULENCE FACTORS, BORDETELLA;

EID: 0034988882     PISSN: 03405761     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002040100230     Document Type: Article

References (41)

1. Safety of intravenous ciprofloxacin. A review
2. Exocytosis in mast cells by basic secretagogues: Evidence for direct activation of GTP-binding proteins
3. i3
4. Mucosal mast cells. I. Isolation and functional characteristics of rat intestinal mast cells
5. Expanded activity and utility of the new fluoroquinolones: A review
6. Natural polyamines stimulate G proteins
7. Pharmacokinetic profile of levofloxacin following once-daily 500-milligram oral or intravenous doses
8. Histamine release from canine lung and liver mast cells induced by radiographic contrast media
9. Histamine-releasing properties of T-3762, a novel fiuoroquinolone antimicrobial agent in intravenous use. I. Effects of doses and infusion rate on blood pressure, heart rate and plasma histamine concentration
10. 1-antihistamines on histamine release from separated canine cutaneous mast cells
11. Role of mast cells, basophils and their mediators in adverse reactions to general anesthetics and radiocontrast media
12. New uses for new and old quinolones and the challenge of resistance
13. Effects of magnesium deficiency on dermal mast cells in rats
14. Agents that release histamine from mast cells
15. Heterogeneity in mast cell populations
16. A phylogenetic study on the occurrence and distribution of histamine in the gastro-intestinal tract and other tissues of man and various animals
17. Mechanism of peptide-induced mast cell degranulation. Translocation and patch-clamp studies
18. Fixation and staining of granules in mucosal mast cells and intraepithelial lymphocytes in the rat jejunum, with special reference to the relationship between the acid glycosaminoglycans in the two cell types
19. Species differences in histamine release induced by fluoroquinolones
20. Characterization of histamine release induced by fluoroquinolone antibacterial agents in-vivo and in-vitro
21. Mechanism of histamine release induced by levofloxacin, a fluoroquinolone antibacterial agent
22. Activation of rat peritoneal mast cells by substance P and mastoparan
23. G protein activation: A receptor-independent mode of action for amphiphilic neuropeptides and venom peptides
24. Plasma histamine and hemodynamic responses following administration of nalbuphine and morphine
25. Effect of ciprofloxacin on histamine release from human and rat mast cells
26. The sites of some histamine-releasing substances in the dog
27. Enantioselective disposition of ofloxacin in humans
28. Functional heterogeneity of mast cells from different species and tissues
29. Anaphylactoid reactions to glycopeptide antibiotics
30. Comparative physiology of histamine
31. Isolation and culture of adult hepatocytes from liver biopsies
32. Comparison of histamine release induced by morphine and oxymorphone administration in dogs
33. Homology of the rat basophilic leukemia cell and the rat mucosal mast cell
34. i GTP-binding proteins linked to a phospholipase C signaling pathway
35. Mast cell heterogeneity: Effects of neuroenteric peptides on histamine release
36. Effects of antacids, ferrous sulphate, and rantidine on absorption of DR-3355 in humans
37. Isolation of histaminecontaining cells from canine fundic mucosa
38. Safety profile of the quinolones
39. 6 resemble those of compound 48/80
40. Mouse 3T3 fibroblasts induce rat basophilic leukemia RBL-2H3) cells to acquire responsiveness to compound 48/80
41. General pharmacology of the new quinolone antibacterial agent levofloxacin