Pitfalls of rapid prenatal diagnosis using the interphase nucleus [2]

Prenatal Diagnosis

Volumn 21, Issue 5, 2001, Pages 419-421

  Liehr, Thomas ^a   Beensen, Volkmar ^a   Hauschild, Rüdiger ^a   Ziegler, Monika ^a   Hartmann, Isabell ^a   Starke, Heike ^a   Heller, Anita ^a   Kähler, Christine ^b   Schmidt, Matthias ^c   Reiber, Wolfgang ^d   Hesse, Martin ^e   Claussen, Uwe ^a  

^a Institut fur Humangenetik und Anthroplogie   (Germany)

^b Klinik für Frauenheilkunde und Geburtshilfe   (Germany)

^c Zentralklinikum Ggmbh Südthüringen ^*  (Germany)

^d Frauenarztpraxis   (Germany)

^e Sudharz Krankenhaus Nordhausen   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AMNIOCENTESIS; AMNION CELL; CASE REPORT; FEMALE; FLUORESCENCE IN SITU HYBRIDIZATION; HUMAN; INTERPHASE; KARYOTYPE; LETTER; OLIGOHYDRAMNIOS; PRENATAL DIAGNOSIS; PRIORITY JOURNAL; RELIABILITY; SEX CHROMOSOME ABERRATION; TRISOMY; TURNER SYNDROME;

ADULT; AMNIOCENTESIS; AMNIOTIC FLUID; CELL NUCLEUS; CHROMOSOME ABERRATIONS; CHROMOSOME BANDING; CHROMOSOME DISORDERS; DIAGNOSTIC ERRORS; FEMALE; GESTATIONAL AGE; HUMANS; IN SITU HYBRIDIZATION, FLUORESCENCE; INTERPHASE; KARYOTYPING; PREDICTIVE VALUE OF TESTS; PREGNANCY; REAGENT KITS, DIAGNOSTIC; REPRODUCIBILITY OF RESULTS;

EID: 0034988105     PISSN: 01973851     EISSN: None     Source Type: Journal    
DOI: 10.1002/pd.44     Document Type: Letter

References (5)

1. A prospective comparative study on fluorescence in situ hybridization (FISH) of uncultured amniocytes and standard karyotype analysis
2. Rapid prenatal diagnosis of aneuploidies in uncultured amniocytes by fluorescence in situ hybridization. Evaluation of > 3,000 cases
3. False-negative finding in rapid interphase FISH analysis of uncultured amniotic cells
4. Overwhelming maternal cell contamination in amniotic fluid samples from patients with oligohydramnios can lead to false prenatal interphase FISH results
5. Translocation trisomy dup(21q) and free trisomy 21 can be distinguished by interphase-FISH