The heterozygous 20210 G/A genotype prevalence in patients affected by central and branch retinal vein occlusion: A pilot study

Graefe's Archive for Clinical and Experimental Ophthalmology

Volumn 239, Issue 4, 2001, Pages 251-256

  Incorvaia, Carlo ^a   Parmeggiani, Francesco ^a   Costagliola, Ciro ^a   Lamberti, Giuseppe ^a   Ferraresi, Paolo ^a   Bernardi, Francesco ^a   Sebastiani, Adolfo ^a  

^a UNIVERSITY OF FERRARA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ADENINE; GUANINE; PROTHROMBIN;

ADULT; AGED; ALLELE; ARTICLE; CONTROLLED STUDY; DISEASE ASSOCIATION; EXON; FEMALE; GENE; GENE AMPLIFICATION; GENE FREQUENCY; GENE MUTATION; GENETIC VARIABILITY; GENOTYPE; HETEROZYGOTE; HUMAN; INCIDENCE; INHERITANCE; ITALY; MAJOR CLINICAL STUDY; MALE; PILOT STUDY; POPULATION; PREVALENCE; PRIORITY JOURNAL; RESTRICTION FRAGMENT; RETINA VEIN OCCLUSION; RETROSPECTIVE STUDY; RISK FACTOR; STATISTICAL ANALYSIS; VEIN THROMBOSIS;

EID: 0034987822     PISSN: 0721832X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004170100266     Document Type: Article

References (49)

1. Retinal vein occlusion and inherited conditions predisposing to thrombophilia
2. Familial thrombophilia and retinal vein occlusion
3. The prothrombin 20210 G to A variation and thrombosis
4. Mutation in the coagulation factor V associated with resistance to activated protein C
5. Protein C, protein S, and antithrombin in acute ocular occlusive diseases
6. The G20210A mutation of the prothrombin gene in patients with previous first episodes of deep vein thrombosis: Prevalence and association with factor V G1691A, methylentetrahydrofolate reductase C677T and plasma prothrombin levels
7. The prothrombin gene G20210A variant: Prevalence in a U.K. anticoagulant clinic population
8. Molecular genetics of venous thromboembolism
9. Familial thrombophilia due to a previously unrecognized mechanism characterized by poor anticoagulant response to activated protein C: Prediction of a cofactor to activated protein C
10. Epidemiology of retinal vein occlusion and its association with glaucoma and increased ocular pressure
11. Nucleotide sequence of the gene for human prothrombin
12. The 20210 A allele of the prothrombin gene is not a risk factor for retinal vein occlusion
13. Is hyperhomocysteinaemia a risk factor for recurrent venous thrombosis?
14. Central vein retinal thrombosis associated with resistance to activated protein C
15. The heterozygous 20210 G/A prothrombin genotype is associated with early venous thrombosis in inherited thrombophilias and is not increased in frequency in artery disease
16. Inherited thrombotic disorders: An update
17. Identification of 15 different candidate causal point mutations and three polymorphism in 19 patients with protein S deficiency using a scanning method for the analysis of the protein S active gene
18. Retinal venous obstructive diseases
19. Heritable thrombophilia and hypofibrinolysis. Possible cause of retinal vein occlusion
20. Identification of eight point mutations in protein S deficiency type I. Analysis of 15 pedigrees
21. Familial dysfibrinogenemia and thrombophilia
22. Idiopathic central retinal vein occlusion in a thrombophilic patient with heterozygous 20210 G/A prothrombin genotype
23. Factor V Leiden and prothrombin 20210 A mutations in patients with central and branch retinal vein occlusion
24. Venous thrombosis due to poor anticoagulant response to activated protein C. Leiden Thrombophilia Study
25. Role of hemostatic gene polymorphisms in venous and arterial thrombotic disease
26. Antithrombin III. Summary of first database update
27. The risk of recurrent thromboembolism in carriers and non-carriers of the G1691A allele in the coagulation factor V gene and the G20210A allele in the prothrombin gene. DURAC Trial Study Group. Duration of Anticoagulation
28. Bilateral retinal vein occlusion associated with 5,10-methylenetetrahydrofolate reductase mutation
29. Thrombin, thrombin inhibitors, and the arterial thrombotic process
30. Increased risk for venous thrombosis in carriers of the prothrombin G ⇒A20210 gene variant
31. A common genetic variation in the 3' untranslated region of the prothrombin gene is associated with elevated plasma prothrombin levels and an increase in venous thrombosis
32. Risk factors for retinal vein occlusions. A case-control study
33. Born to clot: The European burden
34. Three novel mutations in five unrelated subjects with hereditary protein S deficiency type I
35. Protein C deficiency: A database of mutations, 1995 update
36. Risk factors for venous thrombosis: Prevalence, risk, and interaction
37. Geographic distribution of the 20210 G to A prothrombin variant
38. Analysis of genetic polymorphisms related to thrombosis and other risk factors in patients with retinal vein occlusion
39. The prothrombin 20210A allele is the most prevalent genetic risk factor for venous thromboembolism in the Spanish population
40. Arteriovenous crossing as a risk factor in branch retinal vein occlusion
41. Baseline and early natural history report. The central vein occlusion study
42. Risk factors for branch retinal vein occlusion
43. Risk factors for central retinal vein occlusion
44. Risk factors for hemiretinal vein occlusion: Comparison with risk factors for central and branch retinal vein occlusion
45. Venous branch occlusion due to APC resistance
46. Screening for resistance to activated protein C and the mutant gene for factor V:Q506 in patients with central retinal vein occlusion
47. Prevalence of factor V Leiden in patients with retinal vein occlusion
48. Linkage between inherited resistance to activated protein C and factor V gene mutation in venous thrombosis
49. Thrombophilia as a multigenic disease