Antisense inhibition of BRCA1 expression and molecular analysis of hereditary tumors indicate that functional inactivation of the p53 DNA damage response pathway is required for BRCA-associated tumorigenesis

Gynecologic Oncology

Volumn 81, Issue 3, 2001, Pages 441-446

  Reedy, Mark B ^a   Hang, Todd ^a   Gallion, Holly ^a   Arnold, Susanne ^a   Smith, Simon A ^a  

^a UNIVERSITY OF KENTUCKY   (United States)

Author keywords

BRCA1; BRCA2; Hereditary ovarian cancer; TP53 mutations

Indexed keywords

COMPLEMENTARY DNA; DNA; ONCOPROTEIN; PROTEIN P21; PROTEIN P53;

ARTICLE; CARCINOGENESIS; CLINICAL ARTICLE; DNA DAMAGE; FAMILIAL CANCER; GENE INACTIVATION; GENE LOSS; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOBLOTTING; OVARY TUMOR; PRIORITY JOURNAL; SINGLE STRAND CONFORMATION POLYMORPHISM; SOMATIC MUTATION;

EID: 0034985469     PISSN: 00908258     EISSN: None     Source Type: Journal    
DOI: 10.1006/gyno.2001.6190     Document Type: Article

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