In vitro and in vivo expression of a nephritogenic Ig heavy chain determinant: Pathogenic autoreactivity requires permissive light chains

Immunology and Cell Biology

Volumn 79, Issue 3, 2001, Pages 222-230

  Cooperstone, Brenda G ^a   Rahman, Mohammed M ^a   Rudolph, Earl H ^a   Foster, Mary H ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Autoimmunity; Immunoglobulin heavy chain variable region; Immunoglobulin transgene; Nephritogenic immunoglobulin

Indexed keywords

AUTOANTIBODY; COMPLEMENTARY DNA; DNA ANTIBODY; IMMUNOGLOBULIN HEAVY CHAIN; IMMUNOGLOBULIN LIGHT CHAIN; SINGLE STRANDED DNA;

ANIMAL CELL; ANIMAL MODEL; ARTICLE; AUTOIMMUNE DISEASE; AUTOIMMUNITY; CONTROLLED STUDY; FLOW CYTOMETRY; GENE OVEREXPRESSION; GENE REARRANGEMENT; GENETIC RECOMBINATION; IMMUNOGLOBULIN GENE; IMMUNOGLOBULIN VARIABLE REGION; LUPUS ERYTHEMATOSUS NEPHRITIS; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION; SITE DIRECTED MUTAGENESIS; TRANSGENE;

AMINO ACID SEQUENCE; ANIMALS; ANTIBODIES, ANTINUCLEAR; AUTOANTIGENS; B-LYMPHOCYTES; CELL LINE; FLOW CYTOMETRY; GENES, IMMUNOGLOBULIN; HEYMANN NEPHRITIS ANTIGENIC COMPLEX; IMMUNOGLOBULIN HEAVY CHAINS; IMMUNOGLOBULIN LIGHT CHAINS; IMMUNOGLOBULIN M; MEMBRANE GLYCOPROTEINS; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MICE, TRANSGENIC; MOLECULAR SEQUENCE DATA; RECOMBINANT FUSION PROTEINS; SEQUENCE ALIGNMENT; TRANSFECTION;

ANIMALIA; MURINAE;

EID: 0034983365     PISSN: 08189641     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1440-1711.2001.01001.x     Document Type: Article

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