Toxicity study of cefmatilen hydrochloride hydrate (S-1090) (8): Nephrotoxicity study in rabbits by single oral administration

Journal of Toxicological Sciences

Volumn 26, Issue SUPPL. 1, 2001, Pages 149-156

  Kato, I ^a   Ogawa, M ^a   Ueno, M ^a   Nishimura, K ^a   Sato, K ^a   Kii, Y ^a   Muraoka, Y ^a   Hirata, M ^a   Nara, H ^a  

^a SHIONOGI AND CO LTD   (Japan)

Author keywords

Antibiotics; Cefmatilen hydrochloride hydrate; Nephrotoxicity study; Rabbit; S 1090

Indexed keywords

ANTIBIOTIC AGENT; CEFMATILEN; CREATININE; GLUCOSE; PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BODY WEIGHT; CONTROLLED STUDY; CREATININE BLOOD LEVEL; DOSE RESPONSE; DRUG POTENCY; FOOD INTAKE; HISTOPATHOLOGY; KIDNEY TUBULE NECROSIS; NEPHROTOXICITY; NONHUMAN; PROTEIN URINE LEVEL; RABBIT; UREA NITROGEN BLOOD LEVEL;

ANIMALIA; ORYCTOLAGUS CUNICULUS;

EID: 0034981955     PISSN: 03881350     EISSN: 18803989     Source Type: Journal    
DOI: None     Document Type: Article

References (9)

1. Statistics for toxicologists
2. In vitro and in vivo antibacterial activities of S-1090, a new oral cephalosporin
3. Comparison of the renal excretory mechanism of cefmenoxime and other cephalosporins: Effect of paraaminohippurate on renal clearance and intrarenal distribution of cephalosporins in rabbits