Inhibition of human gelatinases by metals released from dental amalgam

Biomaterials

Volumn 22, Issue 14, 2001, Pages 2025-2030

  Souza, A P ^a   Gerlach, R F ^a   Line, S R P ^a  

^a UNIVERSITY OF CAMPINAS   (Brazil)

Author keywords

Dental amalgam; Gelatinases; Metal; MMP; Zinc

Indexed keywords

BIOASSAY; DENTAL COMPOSITES; ENZYME INHIBITION; ENZYMES; TUMORS;

METAL IONS;

DENTAL AMALGAMS;

1,10 PHENANTHROLINE; BUFFER; CHELATING AGENT; COLLAGEN TYPE 1; DENTAL ALLOY; GELATIN; GELATINASE; GELATINASE A; GELATINASE B; MATRIX METALLOPROTEINASE; METAL; METAL ION; ZINC;

ADULT; ARTICLE; CANCER INVASION; COLLAGEN DEGRADATION; CONTROLLED STUDY; DENTAL CARIES; DENTISTRY; ENZYME INHIBITION; EXPLANT; FEMALE; GINGIVA; HUMAN; HUMAN TISSUE; IMMUNOPRECIPITATION; MALE; PERIODONTAL DISEASE; PRIORITY JOURNAL; TEMPOROMANDIBULAR JOINT DISORDER; ZYMOGRAPHY;

ADULT; CATIONS, DIVALENT; CULTURE MEDIA, CONDITIONED; DENTAL AMALGAM; EDETIC ACID; ETHYLMALEIMIDE; FEMALE; GELATINASES; GINGIVA; HUMANS; MALE; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE 9; MIDDLE AGED; PHENANTHROLINES; PHENYLMETHYLSULFONYL FLUORIDE; PROTEASE INHIBITORS; ZINC;

EID: 0034980268     PISSN: 01429612     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0142-9612(00)00388-4     Document Type: Article

References (32)

1. Corrosion of amalgams
2. Corrosion of zinc-containing dental amalgam
3. Corrosion of amalgams with special regard to zinc
4. Penetration of elements from amalgam into dentin
5. Proton microprobe determination of fluorine deph distribution and surface multielement characterization in dental enamel
6. Tissue reaction to the separate implantation of individual constituent phases of dental amalgam, including assessment by energy dispersive X-ray microanalysis
7. Interaction between dental amalgams and the oral environment
8. Role of matrix metalloproteinases in human periodontal diseases
9. Molecular cloning and mRNA tissue distribution of a novel matrix metalloproteinase isolated from porcine enamel organ
10. Doxycycline inhibits neutrophil (PMN)-type matrix metalloproteinases in human adult periodontitis gingiva
11. Matrix metalloproteinases and their inhibitors in gingival crevicular fluid and saliva of periodontitis patients
12. Cytokine-induced endogenous procollagenase stored in the extracellular matrix of soft connective tissue results in a burst of collagen breakdown following its activation
13. A preliminary study of activation of collagenase in carious human dentin matrix
14. Effects of collagenase on root demineralization
15. The activation and function of host matrix metalloproteinases in dentin matrix breakdown in caries lesions
16. Gelatinase A (MMP-2) and cysteine proteinases are essential for the degradation of collagen in soft connective tissue
17. Matrix metalloproteinases (MMP-2 and MMP-9) of the oral cavity; cellular origin and relationship to periodontal status
18. Matrix metalloproteinases and their inhibitor in connective tissue remodeling
19. Relating matrix metalloproteinase structure to function; Why the 'hemopectin' domain?
20. Release of corrosion products from amalgam in phosphate containing solutions
21. The effect of exposure conditions upon the release of soluble copper and tin from dental amalgams
22. Permeability of biological and synthetic molecules through dentine
23. Copper-rich and conventional amalgam restorations after clinical use
24. The in vivo corrosion of dispersalloy
25. Cadmium ions inhibit procollagen C-proteinase and cupric ions inhibit procollagen N-proteinase
26. Metal activation of galactosylhydroxylysyl glucosyltransferase, an intracellular enzyme of collagen biosynthesis
27. Characterization of an inhibitory metal binding site in carboxypeptidase A
28. Mechanism of inhibition of human neutrophil collagenase by gold(I) chrysotherapeutic compounds. Interaction at a heavy metal binding site
29. Evaluation of a dentin barrier test by cytotoxicity testing of various dental cements
30. The biocompatibility of non-amalgam dental filling materials
31. In vitro biocompatibility; a review