Epidermal growth factor regulation of equine glycoprotein hormone α subunit expression in trophoblast cells

Biology of Reproduction

Volumn 65, Issue 1, 2001, Pages 197-203

  Thway, T M ^a   Wolfe, M W ^a  

^a UNIVERSITY OF KANSAS SCHOOL OF MEDICINE   (United States)

Author keywords

Gene regulation; Placenta; Signal transduction; Trophoblast

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; BISINDOLYLMALEIMIDE; EPIDERMAL GROWTH FACTOR; EPIDERMAL GROWTH FACTOR RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; PHORBOL 13 ACETATE 12 MYRISTATE; PROTEIN KINASE C ACTIVATOR;

ALPHA CHAIN; ARTICLE; BASE PAIRING; BETA CHAIN; CELL FUNCTION; CHORIOCARCINOMA; CONTROLLED STUDY; DNA FLANKING REGION; FEMALE; GENE EXPRESSION REGULATION; GENE INDUCTION; HORMONAL REGULATION; HORSE; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROMOTER REGION; SIGNAL TRANSDUCTION; TROPHOBLAST;

EQUIDAE; EQUUS CABALLUS; PRIMATES;

EID: 0034977753     PISSN: 00063363     EISSN: None     Source Type: Journal    
DOI: 10.1095/biolreprod65.1.197     Document Type: Article

References (45)

1. A quantitative immunological assay for pregnant mare serum gonadotrophin
2. Factors influencing pregnant mate serum gonadotrophin production
3. Epidermal growth factor stimulates secretion of human chorionic gonadotropin by cultured human choriocarcinoma cells
4. Differential modulation of human chorionic gonadotropin secretion by epidermal growth factor in normal and malignant placental cultures
5. Transcriptional and posttranscriptional mechanisms in epidermal growth factor regulation of human chorionic gonadotropin (hCG) subunits and hCG receptor gene expression in human choriocarcinoma cells
6. Epidermal growth factor induces differentiation and secretion of human chorionic gonadotropin and placental lactogen in normal human placenta
7. Inhibin and activin modulate the release of gonadotropin-releasing hormone, human chorionic gonadotropin, and progesterone from cultured human placental cells
8. The secretion of human chorionic gonadotropin as well as the alpha- and beta messenger ribonucleic acid levels are stimulated by exogenous gonadoliberin pulses applied to first trimester placenta in a superfusion culture system
9. EGF increases retinoid × receptor-alpha expression in human trophoblastic cells in culture: Relationship with retinoic acid induced human chorionic gonadotropin secretion
10. Effects of diacylglycerol and gonadotropin-releasing hormone on human chorionic gonadotropin release by cultured trophoblast cells
11. Norepinephrine regulates human chorionic gonadotrophin production by first trimester trophoblast tissue in vitro
12. Effects of retinoic acid on differentiation of choriocarcinoma cells in vitro
13. Retinoic acid stimulates placental hormone secretion by choriocarcinoma cell lines in vitro
14. Trophoblast-derived interleukin-1 (IL-1) stimulates the release of human chorionic gonadotropin by activating IL-6 and IL-6-receptor system in first trimester human trophoblasts
15. Trophoblast-derived interleukin-6 (IL-6) regulates human chorionic gonadotropin release through IL-6 receptor on human trophoblasts
16. Interleukin-1 (IL-1-induced IL-6- and IL-6-receptor-mediated release of human chorionic gonadotropin by choriocarcinoma cell lines (Jar and HCCM-5) activates adenosine 3′,5′-monophosphate-independent signal transduction pathway
17. Identification of the horse epidermal growth factor (EGF) coding sequence and its use in monitoring EGF gene expression in the endometrium of the pregnant mare
18. Expression of epidermal growth factor and its receptor in equine placental tissues
19. Characterization of the equine glycoprotein hormone alpha-subunit gene reveals divergence in the mechanism of pituitary and placental expression
20. Functional analysis of the placenta-specific enhancer of the human glycoprotein hormone alpha subunit gene. Emergence of a new element
21. Evolution of placenta-specific gene expression: Comparison of the equine and human gonadotropin alpha-subunit genes
22. The cAMP response elements of the alpha subunit gene bind similar proteins in trophoblasts and gonadotropes but have distinct functional sequence requirements
23. Human chorionic gonadotropin-alpha gene is transcriptionally activated by epidermal growth factor through cAMP response element in trophoblast cells
24. Role of the cyclic AMP response element binding complex and activation of mitogen-activated protein kinases in synergistic activation of the glycoprotein hormone alpha subunit gene by epidermal growth factor and forskolin
25. Differential activation of ERK and JNK mitogen-activated protein kinases by Raf-1 and MEKK
26. Requirement of Ras-GTP-Raf complexes for activation of Raf-1 by protein kinase C
27. 8-Bromo-3′,5′-adenosine monophosphate stimulates the endocrine activity of human cytotrophoblasts in culture
28. Epidermal growth factor but not insulin-like growth factor-I potentiates adenosine 3′,5′-monophosphate-mediated chorionic gonadotropin secretion by cultured human choriocarcinoma cells
29. A role for calcium in gonadotrophin-releasing hormone (GnRH) stimulated secretion of chorionic gonadotrophin by first trimester human placental minces in vitro
30. The interleukin-6 (IL-6)/IL-6-receptor system induces human chorionic gonadotropin production by activating tyrosine kinase-dependent signal transduction pathway different from pathways triggered by protein kinase activators including gonadotropin releasing hormone
31. Different composite regulatory elements direct expression of the human alpha subunit gene to pituitary and placenta
32. Expression of the glycoprotein hormone alpha-subunit gene in the placenta requires a functional cyclic AMP response element, whereas a different cis-acting element mediates pituitary-specific expression
33. Tissue-specific enhancer of the human glycoprotein hormone alpha subunit gene: Dependence on cyclic AMP-inducible elements
34. The gonadotropin alpha-gene contains multiple protein binding domains that interact to modulate basal and cAMP-responsive transcription
35. Regulation of the human chorionic gonadotropin alpha- and beta-subunit promoters by AP-2
36. AP-2 family members regulate basal and cAMP-induced expression of human chorionic gonadotropin
37. The gonadotropin genes: Evolution of distinct mechanisms for hormonal control
38. Regulation of chorionic gonadotropin gene expression
39. Estradiol suppresses phosphorylation of cyclic adenosine 3′,5′-monophosphate response element binding protein (CREB) in the pituitary: Evidence for indirect action via gonadotropin-releasing hormone
40. Promoter elements and transcription factors involved in differentiation-dependent human chorionic gonadotrophin-alpha messenger ribonucleic acid expression of term villous trophoblasts
41. Protein kinase C activates the MEK-ERK pathway in a manner independent of Ras and dependent on Raf
42. How MAP kinases are regulated
43. Immortilization of equine trophoblast cell lines of chorionic girdle cell lineage by simian virus-40 large T- antigen
44. Cyclic AMP and phorbol esters interact synergistically to regulate expression of the chorionic gonadotropin genes
45. Different combinations of regulatory elements may account for expression of the glycoprotein hormone alpha-subunit gene in primate and horse placenta