Evolutionary thinking as a tool in pharmaceutical development

Drug Development Research

Volumn 52, Issue 3, 2001, Pages 439-445

  LeGrand, Edmund K ^a  

^a JOHNSON AND JOHNSON PHARMACEUTICAL RESEARCH AND DEVELOPMENT   (United States)

Author keywords

Acute phase reaction; Apoptosis; Evolution; Pharmaceutical preparations; Reproduction

Indexed keywords

GENE PRODUCT;

ACUTE PHASE RESPONSE; APOPTOSIS; DISEASE CONTROL; DISEASE COURSE; DRUG SCREENING; EVOLUTION; GENE LIBRARY; GENE THERAPY; REPRODUCTION; REVIEW; SYNTHESIS;

EID: 0034974568     PISSN: 02724391     EISSN: None     Source Type: Journal    
DOI: 10.1002/ddr.1145     Document Type: Review

References (4)

1. Ameisen JC. 1994. Programmed cell death (apoptosis) and cell survival regulation: relevance to AIDS and cancer. AIDS 8:1197-1213.
2. Antoni BA, Sabbatini P, Rabson AB, White E. 1995. Inhibition of apoptosis in human immunodeficiency virus-infected cells enhances virus production and facilitates persistent infection. J Virol 69:2384-2392.
3. Beisel WR. 1995. Herman Award Lecture, 1995: infection-induced malnutrition - from cholera to cytokines. Am J Clin Nutr 62: 813-819.
4. Brabin BJ. 1985. Epidemiology of infection in pregnancy. Rev Infect Dis 7:579-603.