Anticocaine catalytic antibodies have no affinity for RTI compounds: Implications for treatment

Synapse

Volumn 41, Issue 2, 2001, Pages 176-178

  Zhang, Li Fen ^a   Moritani, Masayuki ^a   Honma, Shiho ^a   Yoshida, Atsushi ^a   Shigenaga, Yoshio ^a  

^a OSAKA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGEN; CATALYTIC ANTIBODY; COCAINE DERIVATIVE; RTI 112; RTI 177; RTI 51; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BINDING AFFINITY; COCAINE DEPENDENCE; DRUG BINDING; DRUG POTENCY; DRUG SELECTIVITY; ENZYME LINKED IMMUNOSORBENT ASSAY; NONHUMAN; PRIORITY JOURNAL; RAT;

ADRENERGIC UPTAKE INHIBITORS; ANTIBODIES, CATALYTIC; ANTIBODY AFFINITY; BRAIN; CARRIER PROTEINS; COCAINE; COCAINE-RELATED DISORDERS; DRUG THERAPY, COMBINATION; ENZYME-LINKED IMMUNOSORBENT ASSAY; MAZINDOL; TROPANES;

EID: 0034973741     PISSN: 08874476     EISSN: None     Source Type: Journal    
DOI: 10.1002/syn.1072     Document Type: Article

References (15)

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5. Pharmacotherapies for treatment of cocaine abuse: Preclinical aspects
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7. Active immunization with cocaine-protein conjugate attenuates cocaine effects
8. Development of a therapeutic vaccine for the treatment of cocaine addiction
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10. Comparative behavioral pharmacology of cocaine and the selective dopamine uptake inhibitor RTI-113 in the squirrel monkey
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12. A catalytic antibody against cocaine prevents cocaine's reinforcing and toxic effects in rats
13. Self-administration of the high-affinity cocaine analog 2β-carbomethoxy-3 β-(4-fluorophenyl)tropane
14. Reinforcing and discriminative stimulus effects of β-CIT in rhesus monkeys
15. Anti-cocaine catalytic antibodies: A synthetic solution to improved diversity