Modulation of A-NK cell rigidity: In vitro characterization and in vivo implications for cell delivery

Biorheology

Volumn 38, Issue 2-3, 2001, Pages 151-159

  Melder, R J ^a   Kristensen, C A ^a   Munn, L L ^a   Jain, R K ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

Activated lymphocyte; Deformability; Rigidity; Thioglycollate

Indexed keywords

ARTICLE; CANCER IMMUNOTHERAPY; CELL TRANSFER; CYTOSKELETON; HUMAN; HUMAN CELL; LYMPHOCYTE ACTIVATION; NATURAL KILLER CELL; RIGIDITY; VISCOELASTICITY;

ANIMALS; CELL SIZE; COLONIC NEOPLASMS; CYTOCHALASIN D; CYTOSKELETON; CYTOTOXICITY, IMMUNOLOGIC; ELASTICITY; FEMALE; HEMORHEOLOGY; HUMANS; KILLER CELLS, NATURAL; LUNG; LYMPHOCYTE ACTIVATION; MICE; MICE, NUDE; NEOPLASM TRANSPLANTATION; NEOVASCULARIZATION, PATHOLOGIC; THIOGLYCOLATES;

EID: 0034972651     PISSN: 0006355X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (38)

1. Differences in the toxicity and teratogenicity of cytochalasins D and E in various mouse strains
2. Localization of immune effector cells to tumor metastases
3. Tissue distribution of adoptively transferred adherent lymphokine-activated killer cells assessed by different labels
4. Accumulation of adoptively transferred lymphokine activated killer cells in murine metasteses
5. An in vivo study of the role of the tumor cell cytoskeleton in tumor cell-platelet-endothelial cell interactions
6. Fluorescence ratio imaging and optical sectioning: Effect of glucose on spatial and temporal gradients
7. Quantitation and physiological characterization of bFGF and VEGF/VPF induced vessels in mice: Effect of microenvironment on angiogenesis
8. Immunohistological characterization of inflammatory cells that infiltrate tumors
9. TNFa-induced leukocyte-adhesion in normal and tumor vessels: Effect of tumor type, transplantation site and host strain
10. Therapeutic agents for treatment of established metastases and inhibitors of metastatic spread: Preclinical and clinical progress
11. Approaches to immunotherapy with defined populations of IL-2-cultured NK cells, immune T cells or tumor-infiltrating lymphocytes
12. Kinetics of macrophage recruitment and turnover in peritoneal inflammatory exudates induced by Salmonella or thioglycollate broth
13. Delivery of biological molecules and cells to tumors
14. Determinants of tumor blood flow: A review
15. Leukocyte-endothelial adhesion and angiogenesis in tumors
16. In vitro and in vivo quantification of adhesion between leukocytes and vascular endothelium
17. Metabolic inhibitors and intermediate filament organization in human fibroblasts
18. Tissue-isolated human tumor xenografts in athymic nude mice
19. Intratumor pharmacokinetics, flow resistance, and metabolism during gemcitabine infusion in ex vivo perfused human small cell lung cancer
20. Imaging of activated natural killer cells in mice by positron emission tomography: Preferential uptake in tumors
21. Delivery of effector cells to tumors
22. Kinetics of interleukin-2 induced changes in rigidity of human natural killer cells
23. Reduction of rigidity in human activated natural killer cells by thioglycollate treatment
24. During angiogenesis, vascular endothelial growth factor and basic fibroblast growth factor regulate natural killer cell adhesion to tumor endothelium
25. A new approach to generating antitumor effectors for adoptive immunotherapy using human adherent lymphokine-activated killer cells
26. Interleukin 2 induced leukocyte adhesion to the normal and tumor microvascular endothelium in vivo and its inhibition by dextran sulfate: Implications for vascular leak syndrome
27. Low deformability of lymphokine-activated killer cells as a possible determinant of in vivo distribution
28. Preferential localization of human adherent lymphokine-activated killer cells in tumor microcirculation
29. Leukocyte kinetics in the microcirculation
30. Rheology of leukocytes
31. Cell adhesion molecule expression by vascular endothelial cells as an immune/inflammatory reaction in human colon carcinoma
32. Adoptive cellular therapy: Basic principles
33. Vascular endothelial growth factor (VEGF) modulation by targeting HIF-1a->HRE->VEGF cascade differentially regulates vascular response and growth rate in tumors
34. Toxic fungal metabolites in food
35. Antitumor effector cells: Extravasation and control of metastasis
36. Diminished leukocyte-endothelium interaction in tumor microvessels
37. Rolling in P-selectin deficient mice is reduced hut not eliminated in the dorsal skin