Formation of wild-type and chimeric influenza virus-like particles following simultaneous expression of only four structural proteins

Journal of Virology

Volumn 75, Issue 13, 2001, Pages 6154-6165

  Latham, T ^a   Galarza, J M ^a  

^a PFIZER INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GUANINE NUCLEOTIDE BINDING PROTEIN; HEMAGGLUTININ; MATRIX PROTEIN; SIALIDASE; STRUCTURAL PROTEIN;

ANIMAL CELL; ARTICLE; CHIMERA; DENSITY GRADIENT CENTRIFUGATION; ELECTRON MICROSCOPY; GENE EXPRESSION; HYBRID GENE; IMMUNOFLUORESCENCE; IMMUNOGOLD STAINING; INFLUENZA VIRUS; MOLECULAR INTERACTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN LOCALIZATION; VACCINE PRODUCTION; VIRUS ASSEMBLY; VIRUS MORPHOGENESIS; VIRUS PARTICLE; VIRUS RECOMBINANT;

AMINO ACID SEQUENCE; ANIMALS; BACULOVIRIDAE; HEMAGGLUTININ GLYCOPROTEINS, INFLUENZA VIRUS; MICROSCOPY, ELECTRON; MOLECULAR SEQUENCE DATA; NEURAMINIDASE; ORTHOMYXOVIRIDAE; RECOMBINANT FUSION PROTEINS; SPODOPTERA; VIRAL MATRIX PROTEINS; VIRION; VIRUS ASSEMBLY;

EID: 0034972583     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.75.13.6154-6165.2001     Document Type: Article

References (29)

1. Influenza virus assembly: Effect of influenza virus glycoproteins on the membrane association of MI protein
2. Human parainfleunza virus type 1 matrix and nucleoprotein genes transiently expressed in mammalian cells induce the release of virus-like particles containing nucleocapsid-like structures
3. Lodixanol: A nonionic iso-osmotic centrifugation medium for the formation of self-generated gradients
4. Influenza virus NP protein expressed in insect cells by a recombinant baculovirus is associated with a protein kinase activity and possesses single stranded RNA binding activity
5. Virus maturation and budding
6. Assembly and release of HIV-1 precursor pr55 gag virus-like particles from recombinant baculovirus-infected insect cells
7. Efficient formation of influenza virus-like particles: Dependence on the levels of viral proteins
8. Influenza virus matrix protein is the major driving force in virus budding
9. The influenza hemagglutinin cytoplasmic tail is not essential for virus assembly or infectivity
10. Influenza virus hemagglutinin and neuraminidase cytoplasmic tails control particle shape
11. Membrane vesiculation function and exocytosis of wild-type and mutant matrix proteins of vesicular stomatitis virus
12. Papilloma L1 major capsid protein self assembles into virus-like particles that are highly immunogenic
13. Membrane association of influenza virus matrix protein does not require specific hydrophobic domains or the viral glycoproteins
14. Genes and proteins of the influenza viruses
15. Influenza virus M2 protein is an integral membrane protein expressed on the infected-cell surface
16. Viral liposomes released from insect cells infected with recombinant baculovirus expressing the matrix protein of vesicular stomatitis virus
17. Assembly of five BTV proteins expressed by recombinant baculovirus: Inclusion of the largest protein VP1 in the core-like and virus-like particles
18. Nuclear transport of influenza virus ribonucleoproteins: The viral matrix protein (M1) promotes export and inhibits import
19. Budding of rabies virus particles in the absence of the spike glycoproteins
20. A look at assembly and morphogenesis of orthomyxo-and paramyxoviruses
21. Fullerene-like organization of HIV gag protein shell in virus-like particles produced by recombinant baculovirus
22. The M1 and M2 proteins of influenza virus are important determinants in filamentous particle formation
23. Expression of human papillomavirus type 11 L1 protein in insect cells: In vivo and in vitro assembly of virus-like particles
24. Membrane interaction of the influenza virus M1 protein
25. Analysis of human lymphotropic T-cell virus type II-like particle production by recombinant baculovirus-infected insect cells
26. Assembly of SIV virus-like particles containing envelope proteins using a baculovirus expression system
27. Characterization and replicase activity of double-layered and single-layered rotavirus-like particles expressed from baculovirus recombinants
28. Influenza virus assembly in lipid raft microdomains: A role for the cytoplasmic tails of spike glycoproteins
29. The M1 and NP proteins of influenza A virus form homo- but not heterooligomeric complexes when coexpressed in BHK-21 cells