The α-globin gene cluster: Genetics and disorders

Clinical and Investigative Medicine

Volumn 24, Issue 2, 2001, Pages 103-109

  Waye, J S ^a   Chui, D H K ^a  

^a MCMASTER UNIVERSITY MEDICAL CENTRE   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA GLOBIN; BETA GLOBIN; GAMMA GLOBIN; HEMOGLOBIN; HEMOGLOBIN ALPHA CHAIN; HEMOGLOBIN DELTA CHAIN; HEMOGLOBIN GAMMA CHAIN; HEMOGLOBIN H; TRANSCRIPTION FACTOR;

ALPHA THALASSEMIA; ARTICLE; BETA THALASSEMIA; BINDING SITE; CANADA; CHROMOSOME 11; CHROMOSOME 16; DISEASE CARRIER; ERYTHROCYTE; FETUS HYDROPS; GENE CLUSTER; GENE DELETION; GENE EXPRESSION; GENE MUTATION; GENE SEQUENCE; GENETIC DISORDER; GLOBIN GENE; HEMOGLOBINOPATHY; HUMAN; MENTAL DEFICIENCY; POINT MUTATION; PRENATAL DIAGNOSIS; PRIORITY JOURNAL; SCREENING; SICKLE CELL ANEMIA;

ALPHA-THALASSEMIA; GLOBINS; HEMOGLOBINS, ABNORMAL; HUMANS; HYDROPS FETALIS; MULTIGENE FAMILY; MUTATION; ONTARIO; PRENATAL DIAGNOSIS;

EID: 0034971155     PISSN: 0147958X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (28)

1. Sickle cell anemia, a molecular disease
2. Molecular genetics of the human globin genes
3. Prevention and control of haemoglobinopathies
4. Triplicated alpha-globin loci in humans
5. Two different quadruplicated α-globin gene arrangements
6. Human alpha-globin gene expression. The dominant role of the alpha 2-locus in mRNA and protein synthesis
7. A major positive regulatory region located far upstream of the human alpha-globin gene locus
8. Molecular mechanisms of α-thalassemia
9. The alpha thalassemia/mental retardation syndromes
10. Alpha-globin gene organisation in blacks precludes the severe form of alpha-thalassaemia
11. Thalassaemia in Sri Lanka: Implications for the future health burden of Asian populations
12. Prevalence of a-thalassemias in northern Thailand
13. Clinical and laboratory features of the a-thalassemia syndromes
14. Genetic and clinical features of hemoglobin H disease in Chinese patients
15. Hemoglobin H (Hb H) disease in Canada: Molecular diagnosis and review of 110 cases
16. Molecular defects in Hb H hydrops fetalis
17. Homozygous alpha-thalassemia associated with hypospadias in three survivors
18. Hydrops fetalis caused by α-thalassemia: An emerging health care problem
19. FIL)
20. Monosomy for the most telomeric, gene-rich region of human chromosome 16p causes minimal phenotypic effects
21. Genetic modulators of disease
22. Beta-thalassaemia intermedia: Is it possible consistently to predict phenotype from genotype?
23. 0-thalassemia: Important implications for neonatal screening and genetic counseling
24. A guide to the revised antenatal record of Ontario
25. 0-thalassemia deletion
26. Sickle cell disease: No longer a single gene disorder
27. Prevalence and genotypes of alpha- and beta-thalassemia carders in Hong Kong - Implications for population screening