Somatotroph recruitment by glucocorticoids involves induction of growth hormone gene expression and secretagogue responsiveness

Journal of Endocrinology

Volumn 169, Issue 3, 2001, Pages 499-509

  Porter, T E ^a   Dean, C E ^a   Piper, M M ^a   Medvedev, K L ^a   Ghavam, S ^a   Sandor, J ^a  

^a UNIVERSITY OF MARYLAND   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CORTICOSTERONE; GLUCOCORTICOID; GROWTH HORMONE; GROWTH HORMONE RELEASING FACTOR; MESSENGER RNA; PROTIRELIN;

ADENOHYPOPHYSIS; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL COUNT; CELL CULTURE; CELL DIFFERENTIATION; CELL LINEAGE; CELLULAR DISTRIBUTION; CHICKEN; CLINICAL RESEARCH; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CULTURE MEDIUM; EMBRYO; EMBRYO CELL; EMBRYO CULTURE; EMBRYO DEVELOPMENT; EXPOSURE; GENE EXPRESSION; GROWTH HORMONE RELEASE; HEMOLYTIC PLAQUE ASSAY; HORMONE RESPONSE; HORMONE SENSITIVITY; HYPOPHYSIS; HYPOPHYSIS CELL; HYPOTHESIS; IN SITU HYBRIDIZATION; IN VITRO STUDY; IN VIVO STUDY; NONHUMAN; PRIORITY JOURNAL; REVERSE HEMOLYTIC PLAQUE ASSAY; RIBONUCLEASE PROTECTION ASSAY; STAGING; STEM CELL;

ANIMALS; CELL CULTURE TECHNIQUES; CELL DIFFERENTIATION; CHICK EMBRYO; CORTICOSTERONE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GROWTH HORMONE; GROWTH HORMONE-RELEASING HORMONE; HEMOLYTIC PLAQUE TECHNIQUE; IN SITU HYBRIDIZATION; PITUITARY GLAND, ANTERIOR; RNA, MESSENGER; THYROTROPIN-RELEASING HORMONE;

EID: 0034970518     PISSN: 00220795     EISSN: None     Source Type: Journal    
DOI: 10.1677/joe.0.1690499     Document Type: Article

References (35)

1. Determination of adenohypophysis cytodifferentiation during embryonic development
2. Growth hormone-releasing factor stimulates proliferation of somatotrophs in vitro
3. Glucocorticoids regulate the expression of a rat growth hormone gene lacking 5′ flanking sequences
4. Ontogeny of corticosterone-inducible growth hormone-secreting cells during chick embryonic development
5. Function of the homeodomain protein GHF1 in pituitary cell proliferation
6. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
7. Regulation of somatotroph differentiation and growth hormone (GH) secretion by corticosterone and GH-releasing hormone during embryonic development
8. Differential repsonsiveness of somatotrophs to growth hormone-releasing hormone and thyrotropin-releasing hormone during chicken embryonic development
9. Induction of somatotroph differentiation in vivo by corticosterone administration during ckicken embryonic development
10. Functional maturation of somatotropes in fetal rat pituitaries: Analysis by reverse hemolytic plaque assay
11. Fetal rat somatotropes in vitro: Effects of insulin, cortisol, and growth hormone-releasing factor on their differentiation. A light and electron microscopic study
12. Differentiation of fetal rat somatotropes in vitro: Effects of cortisol, 3, 5, 3′-triiodothyronine, and glucagon. A light microscopic and radioimmunological study
13. A tissue-specific transcription factor containing a homeodomain specifies a pituitary phenotype
14. Functional differentiation of the embryonic chicken pituitary gland studied by immunohistological approach
15. Chicken growth hormone cDNA sequence
16. Dwarf locus mutants lacking three pituitary cell types result from mutations in the POU-domain gene Pit-1
17. Pit-1-dependent expression of the receptor for growth hormone-releasing factor mediates pituitary cell growth
18. Uneven regional distributions of prolactin- and growth hormone-secreting cells and sexually dimorphic proportions of prolactin secretors in the adenohypophysis of adult chickens
19. Identification of the blood-borne somatotroph-differentiating factor during chicken embryonic development
20. Detection of hormone release from individual cells in mixed populations using a reverse hemolytic plaque assay
21. Ontogenesis of the three parts of the fetal rat adenohypophysis
22. Dexamethasone induces advanced growth hormone expression in the fetal rat pituitary gland in vitro
23. Studies on the development of growth hormone and prolactin cells in the rat pituitary gland by in situ hybridization
24. Regulation of growth hormone expression in fetal rat pituitary gland by thyroid or glucocorticoid hormone
25. Involvement of glucocorticoid-induced factor(s) in the stimulation of growth hormone expression in the fetal rat pituitary gland in vitro
26. Glucocorticoids enhance stability of human growth hormone mRNA
27. Ontogeny of growth hormone (GH)-secreting cells during chicken embryonic development: Initial somatotrophs are responsive to GH-releasing hormone
28. Evidence that somatotroph differentiation during chicken embryonic development is stimulated by a blood-borne signal
29. Pituitary content and plasma levels of growth hormone in foetal and weanling rats
30. Regulated expression of human growth hormone genes in mouse cells
31. Effect of perinatal hypothyroidism on the developmental regulation of rat pituitary growth hormone and thyrotropin genes
32. Glucocorticoid receptor binding and activation of a heterologous promoter by dexamethasone by the first intron of the human growth hormone gene
33. Detection and measurement of secretion from individual neuroendocrine cells using a reverse hemolytic plaque assay
34. Structure of the chicken growth hormone-encoding gene and its promoter region
35. Functional glucocorticoid inducible enhancer activity in the 5′-flanking sequences of the rat growth hormone gene