High prevalence of FVHR2 polymorphism in Costarician Indians who have no FVL

Thrombosis and Haemostasis

Volumn 85, Issue 6, 2001, Pages 1120-1121

  Herrmann, F H ^a   Salazar Sanchez, L ^a   Jimenez Arce, G ^a   Grimm, R ^a   Schroder W ^a  

^a UNIVERSITY OF GREIFSWALD   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BLOOD CLOTTING FACTOR 5; BLOOD CLOTTING FACTOR 5 LEIDEN;

ALLELE; CONSANGUINITY; CONTROLLED STUDY; COSTA RICA; GENE MUTATION; GENETIC POLYMORPHISM; GENOTYPE; HAPLOTYPE; HETEROZYGOTE; HIGH RISK POPULATION; HOMOZYGOSITY; HOMOZYGOTE; HUMAN; INDIAN; LETTER; MAJOR CLINICAL STUDY; PREVALENCE; PRIORITY JOURNAL; VEIN THROMBOSIS;

EID: 0034966462     PISSN: 03406245     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-0037-1615976     Document Type: Letter

References (7)

1. A factor V gene component differing from factor V R506Q contributes to the activated protein C resistance phenotype
2. Detection of new polymorphic markers in the factor V gene: Association with factor V levels in plasma
3. Prevalence of factor V Leiden mutation in various populations
4. Mutation in blood coagulation factor V associated with resistance to activated protein C
5. A new factor V gene polymorphism (His 1255 Arg) present in subjects of african origin mimics the R2 polymorphism (His 1299 Arg)
6. Factor V HR2: An ancient haplotype out of Africa - Reasons for being interested
7. Coinheritence of HR2 haplotype in the factor V gene confers an increased risk of venous thromboembolism to carriers of factor V R506Q (factor V Leiden)