K-ras mutation at codon 12 in stage I pancreatic adenocarcinoma: Analysis by laser capture microdissection and direct sequencing

Journal of the Formosan Medical Association

Volumn 100, Issue 5, 2001, Pages 352-354

  Chang, M C ^a   Chang, Y T ^a   Wu, M S ^a   Shun, C T ^a   Tien, Y W ^a   Lin, J T ^a  

^a NATIONAL TAIWAN UNIVERSITY HOSPITAL   (Taiwan)

Author keywords

K ras mutation; Laser capture microdissection; Pancreatic adenocarcinoma

Indexed keywords

ADENINE; GUANINE; THYMINE;

ADULT; AGED; ARTICLE; CANCER CELL; CANCER STAGING; CARCINOGENESIS; CLINICAL ARTICLE; CODON; CONTROLLED STUDY; EASTERN HEMISPHERE; FEMALE; GENE MUTATION; GENE SEQUENCE; GENETIC ANALYSIS; GEOGRAPHY; HUMAN; HUMAN TISSUE; LASER CAPTURE MICRODISSECTION; MALE; MUTATION RATE; NUCLEIC ACID BASE SUBSTITUTION; ONCOGENE K RAS; PANCREAS ADENOCARCINOMA; PANCREAS DUCT; PANCREATICODUODENECTOMY; POLYMERASE CHAIN REACTION; SENSITIVITY AND SPECIFICITY; TECHNIQUE; TISSUE SECTION; WESTERN HEMISPHERE;

ADENOCARCINOMA; ADULT; AGED; CELL SEPARATION; CODON; FEMALE; GENES, RAS; HUMANS; LASERS; MALE; MIDDLE AGED; PANCREATIC NEOPLASMS; POINT MUTATION; SEQUENCE ANALYSIS; TUMOR MARKERS, BIOLOGICAL;

EID: 0034966321     PISSN: 09296646     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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2. Most human carcinomas of the exocrine pancreas contain mutant c-K-ras genes
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7. Laser capture microdissection of single cells from complex tissues
8. Laser-assisted microdissection: Application in molecular pathology
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10. Detection of ras gene mutations in pancreatic juice and peripheral blood of patients with pancreatic adenocarcinoma
11. Diagnostic utility of K-ras mutations in fine-needle aspirates of pancreatic masses
12. Molecular pathology of invasive carcinoma
13. K-ras mutation is an early event in pancreatic duct carcinogenesis in the Syrian golden hamster