Population genetics of factor V Leiden in Europe

Blood Cells, Molecules, and Diseases

Volumn 27, Issue 2, 2001, Pages 362-367

  Lucotte, Gérard ^a   Mercier, Géraldine ^b  

^a Intl Institute of Anthropology   (France)

^b European Laboratory of Screening   (France)

Author keywords

APC resistance; Frequency of factor V Leiden mutation; Neolithic farmers migration; Origin and distribution of the mutation; Populations in Europe

Indexed keywords

BLOOD CLOTTING FACTOR 5;

ARTICLE; EUROPE; GENE FREQUENCY; GENE MUTATION; GENETIC RISK; GEOGRAPHIC DISTRIBUTION; HUMAN; POPULATION GENETICS; PRIORITY JOURNAL; THROMBOEMBOLISM;

EID: 0034965498     PISSN: 10799796     EISSN: None     Source Type: Journal    
DOI: 10.1006/bcmd.2001.0388     Document Type: Article

References (40)

1. Mutation in blood coagulation factor V associated with resistance to activated protein C
2. Familial thrombophilia due to a previously unrecognized mechanism characterized by poor anticoagulant response to activated protein C: Prediction of a cofactor to activated protein C
3. World distribution of factor V Leiden
4. Prevalence of factor V gene mutation amongst myocardial infarction patients and healthy controls is higher in Sweden than in other countries
5. The population genetics of factor V Leiden (Arg506Gln)
6. World distribution of factor V Leiden
7. Factor V Leiden: Prevalence in the indigenous population and cases of thrombosis in north India
8. Detection of new polymorphic markers in the factor V gene: Association with factor V levels in plasma
9. Evidence for a single origin of factor V Leiden
10. A single genetic origin for a common Caucasian risk factor for venous thrombosis
11. New coagulation factor V gene polymorphisms define a single and infrequent haplotype underlying the factor V Leiden mutation in Mediterranean populations and Indians
12. World distribution of factor V Leiden mutation
13. Frequency of factor VQ506 and prothrombin 20210A mutations in an apparently health Icelandic population and patients suffering from venous thrombosis
14. Arg506Gln factor V mutation (factor V Leiden) in patients with ischaemic cerebrovascular disease and survivors of myocardial infarction
15. Myocardial infarction, arg 506 to gln factor V mutation, and activated protein C resistance
16. High prevalence of a mutation in the factor V gene within the U. K. population: Relationship to activated protein C resistance and familial thrombosis
17. High risk of thrombosis in patients homozygous for factor V Leiden (activated protein C resistance)
18. World distribution of factor V mutation
19. High prevalence of factor VR506Q mutation in German thrombophilic and normal population
20. Population study of the G1691A mutation (R506Q, FV Leiden) in the human factor V gene that is associated with resistance to activated protein C
21. Frequency of factor V Leiden (Arg506Gln) in France
22. Factor V Leiden mutation is not a major cause of thrombotic tendency in essential thrombocythemia polycythemia vera
23. Prevalence of factor V Leiden (Arg506Gln) in Hungary
24. Frequency of factor V Arg506Gln in Italians
25. Prevalence of factor V Leiden mutation in non-European populations
26. Prevalence of mutated factor V Arg506 to Gln in Italians
27. Polymorphisms of fibrinogen, factor VIII and factor V genes. Comparison of allele frequencies in different ethnic groups
28. Factor V Leiden (R506Q) and risk of venous thromboembolism: A case-control study based on the Spanish population
29. Prevalence of the FVQ506 mutation in the Hellenic population
30. Frequency of factor V Leiden in Turkey
31. Frequency of factor V (1691G → A) mutation in Turkish population
32. Prevalence of the FVQ506 (factor V Leiden) mutation in the normal and thrombophilic Algerian population
33. Genes and languages in Europe: An analysis of mitochondrial lineages
34. Y-chromosome DNA haplotypes in Basques
35. Activated protein C (APC) resistance: Does it exist in Basques?
36. Frequency of factor V Leiden (Arg506Gln) in Turkey
37. Reconstruction of human evolution: Bringing together genetic, archaelogical and linguistic data
38. Demic expansions and human evolution