Characterization of crosslinking sites in fibrinogen for plasminogen activator inhibitor 2 (PAI-2)

Annals of the New York Academy of Sciences

Volumn 936, Issue , 2001, Pages 215-218

  Ritchie, Helen ^a   Lawrie, Laura C ^a   Mosesson, Michael W ^b   Booth, Nuala A ^a,c  

^a UNIVERSITY OF ABERDEEN   (United Kingdom)

^b BLOOD RESEARCH INSTITUTE   (United States)

^c UNIVERSITY OF ABERDEEN   (United Kingdom)

Author keywords

A chain; Crosslinking; Fibrinogen; Fibrinolysis; PAI 2; Plasminogen activator inhibitor 2; Transglutaminase

Indexed keywords

ALPHA 2 ANTIPLASMIN; BLOOD CLOTTING FACTOR 13A; FIBRINOGEN; LYSINE; PLASMINOGEN ACTIVATOR INHIBITOR 2; PROTEIN GLUTAMINE GAMMA GLUTAMYLTRANSFERASE; SERINE PROTEINASE INHIBITOR;

ALPHA CHAIN; AMINO ACID SEQUENCE; CONFERENCE PAPER; FIBRINOLYSIS; MASS SPECTROMETRY; PROTEIN CROSS LINKING;

EID: 0034964394     PISSN: 00778923     EISSN: None     Source Type: Book Series    
DOI: 10.1111/j.1749-6632.2001.tb03508.x     Document Type: Conference Paper

References (13)

1. Biological and clinical aspects of plasminogen activator inhibitor type 2
2. Thrombin modulates synthesis of plasminogen activator inhibitor 2 (PAI-2) by human peripheral blood monocytes
3. Secretion of plasminogen activator inhibitor 2 by human peripheral blood monocytes occurs via an endoplasmic reticulum-Golgi-independent pathway
4. Type-2 plasminogen activator inhibitor is a substrate for trophoblast transglutaminase and factor XIIIa-transglutaminase-catalyzed cross linking to cellular and extracellular structures
5. Monocyte plasminogen activator inhibitor 2 (PAI-2) inhibits u-PA-mediated fibrinolysis and is cross-linked to fibrin
6. Cross-linking site in fibrinogen for α2-plasmin inhibitor
7. Cross-linking of plasminogen activator inhibitor 2 and α2-antiplasmin to fibrin(ogen)
8. The crystal structure of modified bovine fibrinogen
9. Crystal structures of fragment D from human fibrinogen and its crosslinked counterpart from fibrin
10. Sites in fibrin involved in the acceleration of plasminogen activation by tPA. Possible role of fibrin polymerization
11. 2-antiplasmins to fibrin by activated factor XIII and by a tissue transglutaminase
12. α2-plasmin inhibitor is a substrate for tissue transglutaminase: An in vitro study
13. Fibrin as a factor in atherogenesis