Efficacy and safety of an intravenous monoclonal anti-HBs in chronic hepatitis B patients

Liver

Volumn 21, Issue 3, 2001, Pages 207-212

  Van Nunen, Andeltje B ^a   Baumann, Matthias ^b   Manns, Michael P ^c   Reichen, J ^d   Spengler, U ^e   Marschner, Jens Peter ^b   De Man, Robert A ^a  

^a ERASMUS MEDICAL CENTER   (Netherlands)

^b F HOFFMANN LA ROCHE LTD   (Switzerland)

^c HANNOVER MEDICAL SCHOOL   (Germany)

^d UNIVERSITY OF BERN   (Switzerland)

^e UNIVERSITY OF BONN   (Germany)

Author keywords

Hepatitis B; Monoclonal antibody; Treatment

Indexed keywords

ALPHA INTERFERON; ANTIVIRUS AGENT; HEPATITIS B SURFACE ANTIBODY; HEPATITIS B SURFACE ANTIGEN; MONOCLONAL ANTIBODY; OST 577; RECOMBINANT ALPHA2B INTERFERON; TUVIRUMAB; UNCLASSIFIED DRUG; VIRUS DNA;

ABDOMINAL PAIN; ADULT; ADVERSE DRUG REACTION; ANTIGEN ANTIBODY COMPLEX; ARTHRALGIA; ARTICLE; CHILL; CIRCULATION; CLINICAL ARTICLE; CLINICAL TRIAL; COMBINATION CHEMOTHERAPY; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG EFFICACY; DRUG SAFETY; DYSPNEA; FEMALE; FEVER; FLU LIKE SYNDROME; HEMATURIA; HEPATITIS B; HUMAN; LEUKOPENIA; LOW BACK PAIN; MALE; MONOTHERAPY; PROTEINURIA; RISK; SEROCONVERSION; SERUM; SOLUBILITY; SYNCOPE; TINNITUS; VIRUS LOAD;

ADULT; ANTIBODIES, MONOCLONAL; ANTIVIRAL AGENTS; DRUG THERAPY, COMBINATION; FEMALE; HEPATITIS B SURFACE ANTIGENS; HEPATITIS B VACCINES; HEPATITIS B, CHRONIC; HUMANS; INJECTIONS, INTRAVENOUS; INTERFERON ALFA-2B; MALE; MIDDLE AGED; TREATMENT FAILURE;

EID: 0034961551     PISSN: 01069543     EISSN: None     Source Type: Journal    
DOI: 10.1034/j.1600-0676.2001.021003207.x     Document Type: Article

References (21)

1. Effect of alpha-interferon treatment in patients with hepatitis B e antigen-positive chronic hepatitis
2. Alpha interferon for chronic hepatitis B infection: Increased efficacy of prolonged treatment
3. The treatment effect of alpha interferon in chronic hepatitis B is independent of pre-treatment variables. Results based on individual patient data from 10 clinical controlled trials
4. A one-year trial of lamivudine for chronic hepatitis B
5. Lamivudine and alpha interferon combination treatment of patients with chronic hepatitis B infection: A randomised trial
6. Lamivudine resistance in immunocompetent chronic hepatitis B: Incidence and patterns
7. Long-term application of human hepatitis-B immunoglobulin to prevent hepatic allograft infection
8. Liver transplantation in European patients with the hepatitis B surface antigen
9. Hepatitis B vaccine and anti-HBs complex as approach for vaccine therapy
10. Infusion of hepatitis B antibody in antigen-positive active chronic hepatitis
11. Monoclonal antibody to HBsAg for chronic hepatitis B virus infection with hypogammaglobulinaemia
12. Human ×(Mouse× Human) hybridomas stable producing human antibodies
13. Human monoclonal antibody against hepatitis B surface antigen in preventing recurrent hepatitis B following liver transplantation
14. Human monoclonal antibodies in transplantation
15. Structure and molecular virology
16. Characterisation of human monoclonal antibodies directed against hepatitis B surface antigen
17. Prevention of hepatitis B virus carrier state in infants according to maternal serum levels of HBV DNA
18. Hepatitis B immune globulin (HBIg) efficacy in the interruption of perinatal transmission of hepatitis B virus carrier state
19. Immunization against hepatitis B virus by mucosal administration of antigen-antibody complexes
20. Modulation of the immunological response to hepatitis B virus by antibodies