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Volumn 31, Issue 5, 2001, Pages 239-248

Metabolism of amiodarone (part III): Identification of rabbit cytochrome p450 isoforms involved in the hydroxylation of mono-N-desethylamiodarone

(5) Kozlik, P a Ha, H R a Stieger, B a Bigler, L a Follath, F a

a UNIVERSITY HOSPITAL ZURICH (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA NAPHTHOFLAVONE; AMIODARONE; CIMETIDINE; CYCLOSPORIN A; CYTOCHROME P450; CYTOCHROME P450 1A; CYTOCHROME P450 2C; CYTOCHROME P450 2D; CYTOCHROME P450 3A6; CYTOCHROME P450 INHIBITOR; DEETHYLAMIODARONE; MIDAZOLAM; N 3 HYDROXYBUTYL DEETHYLAMIODARONE; QUINIDINE; RIFAMPICIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL CULTURE; CONTROLLED STUDY; DRUG HYDROXYLATION; DRUG METABOLISM; DRUG STRUCTURE; DRUG TRANSFORMATION; ENZYME SUBSTRATE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LIVER MICROSOME; MICHAELIS MENTEN KINETICS; NONHUMAN; QUANTITATIVE ASSAY; RABBIT;

AMIODARONE; ANIMALS; ANTI-ANXIETY AGENTS; ANTI-ARRHYTHMIA AGENTS; ARYL HYDROCARBON HYDROXYLASES; BENZOFLAVONES; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CIMETIDINE; CYCLOSPORINE; CYTOCHROME P-450 CYP3A; CYTOCHROME P-450 ENZYME SYSTEM; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; KETOCONAZOLE; KINETICS; MICROSOMES, LIVER; MIDAZOLAM; MODELS, CHEMICAL; OXIDOREDUCTASES, N-DEMETHYLATING; PROTEIN ISOFORMS; QUINIDINE; RABBITS; RIFAMPIN; TIME FACTORS;

ANIMALIA; ORYCTOLAGUS CUNICULUS;

EID: 0034960158 PISSN: 00498254 EISSN: None Source Type: Journal
DOI: 10.1080/00498250110046442 Document Type: Article

Times cited : (10)

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