Hypomorphic phenotype in mice with pituitary-specific knockout of steroidogenic factor 1

Genesis (United States)

Volumn 30, Issue 2, 2001, Pages 65-69

  Zhao, Liping ^a   Bakke, Marit ^a   Krimkevich, Yelena ^a   Cushman, Lisa J ^b   Parlow, A F ^a,b,c   Camper, Sally A ^b   Parker, Keith L ^a  

^a UNIVERSITY OF TEXAS AT DALLAS   (United States)

^b UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^c HARBOR UCLA MEDICAL CENTER   (United States)

Author keywords

Cre recombinase; Gonadotropins; Hypogonadotropic hypogonadism; Orphan nuclear receptors; Tissue specific knockout

Indexed keywords

CRE RECOMBINASE; STEROIDOGENIC FACTOR 1;

ADENOHYPOPHYSIS; ALLELE; ALPHA CHAIN; ARTICLE; BACTERIOPHAGE; GENE INACTIVATION; GENOTYPE; GONAD FUNCTION; HYPOGONADOTROPIC HYPOGONADISM; HYPOPLASIA; IN VIVO STUDY; INFERTILITY; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; TISSUE SPECIFICITY; TRANSGENE;

EID: 0034959894     PISSN: 1526954X     EISSN: None     Source Type: Journal    
DOI: 10.1002/gene.1034     Document Type: Article

References (9)

1. Cre-mediated recombination in the pituitary gland
2. An Fgf8 mutant allelic series generated by Cre- and Flp-mediated recombination
3. Ad4BP/SF-1, a transcription factor essential for the transcription of steroidogenic cytochrome P450 genes and for the establishment of the reproductive function
4. Cre recombinase: The universal reagent for genome tailoring
5. Steroidogenic factor 1: An essential mediator of endocrine development and function
6. DNA excision in liver by an albumin-Cre transgene occurs progressively with age
7. Mutations of gonadotropins and gonadotropin receptors: Elucidating the physiology and pathophysiology of pituitary-gonadal functions
8. An inactivating mutation of the luteinizing hormone receptor causes amenorrhea in a 46, XX female
9. Steroidogenic factor 1 (SF1) is essential for pituitary gonadotrope function