Effect of astaxanthin on the hepatotoxicity, lipid peroxidation and antioxidative enzymes in the liver of CCl4-treated rats

Methods and Findings in Experimental and Clinical Pharmacology

Volumn 23, Issue 2, 2001, Pages 79-84

  Kang, J O ^a   Kim, S J ^a   Kim, H ^a  

^a Kyung Hee University   (South Korea)

Author keywords

Antioxidation; Astaxanthin; Lipid peroxidation

Indexed keywords

ALANINE AMINOTRANSFERASE; ANTIOXIDANT; ASPARTATE AMINOTRANSFERASE; ASTAXANTHIN; CARBON TETRACHLORIDE; CAROTENOID; ENZYME; GLUTATHIONE; GLUTATHIONE PEROXIDASE; GLUTATHIONE REDUCTASE; SUPEROXIDE DISMUTASE; THIOBARBITURIC ACID REACTIVE SUBSTANCE;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; ENZYME ACTIVITY; LIPID PEROXIDATION; LIVER PROTECTION; LIVER TOXICITY; LIVER WEIGHT; MALE; NONHUMAN; RAT;

EID: 0034959030     PISSN: 03790355     EISSN: None     Source Type: Journal    
DOI: 10.1358/mf.2001.23.2.627931     Document Type: Article

References (28)

1. Carotenoids as singlet oxygen quenchers in marine organisms
2. Effects of canthaxanthin, astaxanthin, lycopene and lutein on liver xenobiotic-metabolizing enzymes in the rat
3. Lycopene as the most efficient biological carotenoid singlet oxygen quencher
4. Astaxanthin: Antioxidant effects in chicken embryo fibroblasts
5. Antioxidant activity of xanthophylls on peroxyl radical-mediated phospholipid peroxidation
6. Effects of carotenoids in cellular and animal systems
7. Chemoprevention of rat oral carcinogenesis by naturally occurring xanthophylls, astaxanthin and canthaxanthin
8. Suppression of azoxymethane-induced rat colon carcinogenesis by dietary administration of naturally occurring xanthophylls astaxanthin and canthaxanthin during the postinitiation phase
9. Antioxidant functions of vitamins. Vitamins E, and C, β-carotene, and other carotenoids
10. Hyperbaric oxygen protection against carbon tetrachloride hepatotoxicity in the rat
11. The involvement of Kupffer cells in carbon tetrachloride toxicity
12. Influence of calcium ions on mammalian intramitochondrial dehydrogenases
13. Glutathione and glutathione disulfide
14. Assay for lipid peroxidation in animal tissues by thiobarbituric acid reaction
15. The role of superoxide anion in the autoxidation of epinephrine and a simple assay for superoxide dismutase
16. Glutathione peroxidase and hydroperoxides
17. Glutathione reductase
18. Protein measurement with the folin phenol reagent
19. Prevention by cystamine of liver necrosis and early biochemical alterations induced by carbon tetrachloride
20. 4-induced hepatic inflammation and fibrosis in rats
21. Kupffer cell stimulation with Corynebacterium parvum reduces some cytochrome P450-dependent activities and diminishes acetaminophen and carbon tetrachloride-induced liver injury in the rat
22. Glutathione depletion and susceptibility
23. Reaction of glutathione with a free radical metabolite of carbon tetrachloride
24. 4-induced cirrhosis of the rats
25. Potent protective effect of melatonin on in vivo paraquat-induced oxidative damage in rats
26. Effect of chronic ethanol feeding on lipid peroxidation and protein oxidation in relation to liver pathology
27. 4-induced erythrocyte damage in rats
28. Acute ethanol exposure alters hepatic glutathione metabolism in riboflavin deficiency