Acrylic resins as rate-controlling membranes in novel formulation of a nine-day 17β-estradiol transdermal delivery system: In vitro and release modifier effect evaluation

Drug Development and Industrial Pharmacy

Volumn 27, Issue 5, 2001, Pages 431-437

  Rafiee Tehrani, M ^a   Safaii Nikui, N ^a   Peteriet, H ^a   Beckert, T ^a  

^a TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

Estradiol; In vitro dissolution testing; Polyacrylates; Release modifiers; Transdermal drug delivery

Indexed keywords

ACRYLIC ACID RESIN; CITRIC ACID TRIBUTYL ESTER; CITRIC ACID TRIETHYL ESTER; ESTRADIOL; MYRISTIC ACID; PLASTICIZER; PROPYLENE GLYCOL;

ARTICLE; DRUG DELIVERY SYSTEM; DRUG FORMULATION; DRUG RELEASE; DRUG SOLUBILITY; EVALUATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; KINETICS;

ACRYLIC RESINS; ADMINISTRATION, CUTANEOUS; DRUG DELIVERY SYSTEMS; ESTRADIOL; FEASIBILITY STUDIES; FEMALE; HORMONE REPLACEMENT THERAPY; HUMANS; PROPYLENE GLYCOL; SOLUBILITY; TIME FACTORS;

EID: 0034958030     PISSN: 03639045     EISSN: None     Source Type: Journal    
DOI: 10.1081/DDC-100104318     Document Type: Article

References (24)

1. Rate-control drug delivery system: Controlled release versus sustained release
2. Transdermal dual-controlled delivery of testosterone and estradiol: Impact of system design
3. Treatment of hot flashes with transdermal estradiol administration
4. Comparison of the effects of oral and transdermal estradiol administration on oestrogen metabolism, protein synthesis, gonadotrophin release, bone turnover and climacteric symptoms in postmenopausal women
5. Preventive effects of transdermal of 17β-estradiol on postmenopausal bone loss: A two-year prospective study
6. Preventive effects of transdermal 17β-estradiol on osteoporotic changes after surgical menopause: A two-year placebo-controlled trial
7. Pharmacokinetics of estradiol, free and total estrone, in young women following single intravenous and oral administration of 17β-estradiol
8. Comparative serum estradiol profiles from a new once-a-week transdermal estradiol patch and a twice-a-week transdermal estradiol patch
9. Plasma profiles of transdermal 17β-estradiol delivered by two different matrix patches
10. Comparative in vitro release profiles of marketed nitroglycerin batches by different dissolution methods
11. Vehicular influence on transdermal drug penetration
12. Transdermal enhancer patent literature
13. Enhanced transdermal delivery of estradiol in vitro using binary vehicles of isopropyl myristate and short-chain alkanols
14. Acrylic resins as rate-controlling membranes in delivery unilaminate device of estradiol
15. Effect of plasticizers and enhancers on release behavior of estradiol from unilaminate TDD Patch
16. Solubilization of steroids by multiple co-solvent systems
17. Macromolecular structure and solute diffusion in membranes: An overview of recent theories
18. Effect of topical vehicle composition on the in vitro release of fluocinolone acetonide and its acetate ester
19. Increased skin permeability for lipophilic molecules
20. Transdermal oxymorphone formulation development and methods for evaluating flux and lag times for two skin enhancing vehicles