Immunohistochemical and ultrastructural studies of 2,6-dimethylaniline-induced nasal proliferative lesions in a rat two-stage nasal carcinogenesis model initiated with n-bis(2-hydroxypropyl)nitrosamine

Toxicologic Pathology

Volumn 29, Issue 3, 2001, Pages 300-307

  Koujitani, Takatoshi ^a   Yasuhara, Kazuo ^a   Toyosawa, Kaoru ^b   Shimada, Akinori ^c   Onodera, Hiroshi ^a   Takagi, Hisayoshi ^a   Tamura, Toru ^a   Hirose, Masao ^a   Mitsumori, Kunitoshi ^a,d  

^a NATIONAL INSTITUTE OF HEALTH SCIENCES   (Japan)

^b DAINIPPON SUMITOMO PHARMA CO LTD   (Japan)

^c TOTTORI UNIVERSITY   (Japan)

^d TOKYO UNIVERSITY OF AGRICULTURE AND TECHNOLOGY   (Japan)

Author keywords

2,6 dimethylaniline; Bowman's gland; Carcinogenicity; N bis(2 hydroxypropyl)nitrosamine; Nasal cavity; Proliferative lesions; Rat

Indexed keywords

2,6 DIMETHYLANILINE; ANILINE DERIVATIVE; BIS(2 HYDROXYPROPYL)NITROSAMINE; COLLAGEN TYPE 4; CYTOKERATIN; NEUROFILAMENT PROTEIN; UNCLASSIFIED DRUG; VIMENTIN; XYLAZINE;

ADENOMA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL ULTRASTRUCTURE; CHEMICAL CARCINOGENESIS; CONTROLLED STUDY; DYSPLASIA; HISTOPATHOLOGY; HYPERPLASIA; IMMUNOHISTOCHEMISTRY; MALE; NONHUMAN; NOSE CANCER; NOSE CARCINOMA; NOSE CAVITY; OLFACTORY EPITHELIUM; PRIORITY JOURNAL; RAT; SECRETORY GRANULE;

ADENOMA; ANILINE COMPOUNDS; ANIMALS; BASEMENT MEMBRANE; CARCINOGENS; CARCINOMA; COLLAGEN TYPE IV; DESMOSOMES; DIET; DISEASE MODELS, ANIMAL; DRUG COMBINATIONS; IMMUNOENZYME TECHNIQUES; INJECTIONS, SUBCUTANEOUS; INTERMEDIATE FILAMENT PROTEINS; MALE; NITROSAMINES; NOSE NEOPLASMS; OLFACTORY MUCOSA; PRECANCEROUS CONDITIONS; RATS; RATS, INBRED F344; SECRETORY VESICLES;

ANIMALIA;

EID: 0034956411     PISSN: 01926233     EISSN: None     Source Type: Journal    
DOI: 10.1080/019262301316905255     Document Type: Article

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