Metastasizing neuroblastomas from taste buds in rats transgenic for the simian virus 40 large t antigen under control of the probasin gene promoter

Toxicologic Pathology

Volumn 29, Issue 3, 2001, Pages 363-368

  Asamoto, Makoto ^a   Hokaiwado, Naomi ^a   Cho, Young Man ^a   Ikeda, Yoshihisa ^a   Takahashi, Satoru ^a   Shirai, Tomoyuki ^a  

^a NAGOYA CITY UNIV MEDICAL SCHOOL   (Japan)

Author keywords

Androgen independent; Endocrine carcinoma; Pgp9.5; Small cell carcinoma; Synaptophysin; Tongue

Indexed keywords

HYDROLASE; PROBASIN; SYNAPTOPHYSIN; TESTOSTERONE PROPIONATE; UBIQUITIN; VIRUS LARGE T ANTIGEN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CASTRATION; CONTROLLED STUDY; IMMUNOHISTOCHEMISTRY; MALE; METASTASIS; NEUROBLASTOMA; NEUROEPITHELIUM; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROSTATE; PROTEIN EXPRESSION; RAT; SIMIAN VIRUS 40; SMALL CELL SARCOMA; SPINAL CORD; TASTE BUD; TONGUE; TRANSGENIC ANIMAL;

ANDROGEN-BINDING PROTEIN; ANIMALS; ANIMALS, GENETICALLY MODIFIED; ANTIGENS, DIFFERENTIATION; ANTIGENS, VIRAL, TUMOR; FEMALE; IMMUNOHISTOCHEMISTRY; KERATINS; LUNG NEOPLASMS; MALE; NEUROBLASTOMA; PREGNANCY; PROMOTER REGIONS (GENETICS); PROSTATIC NEOPLASMS; RATS; RATS, SPRAGUE-DAWLEY; SIMIAN VIRUS 40; SPINAL CORD NEOPLASMS; SYNAPTOPHYSIN; TASTE BUDS; TONGUE NEOPLASMS; UBIQUITIN THIOLESTERASE;

ANIMALIA; SIMIAE; SIMIAN VIRUS; SIMIAN VIRUS 40;

EID: 0034956382     PISSN: 01926233     EISSN: None     Source Type: Journal    
DOI: 10.1080/019262301316905327     Document Type: Article

References (27)

1. Transgenic models of tumor development
2. Transgenic rats carrying human c-Ha-ras proto-oncogenes are highly susceptible to N-methyl-N-nitrosourea mammary carcinogenesis
3. Use of animal models in defining efficacy of chemoprevention agents against prostate cancer
4. Transgenic mice harboring SV40 T-antigen genes develop characteristic brain tumors
5. Slight promotion effects of intermittent administration of testosterone propionate and/or diethylstilbestrol on 3,2′-dimethyl-4 -aminobiphenyl-initiated rat prostate carcinogenesis
6. SV40 large tumor antigen forms a specific complex with the product of the retinoblastoma susceptibility gene
7. Characterization and cloning of rat dorsal prostate mRNAs. Androgen regulation of two closely related abundant mRNAs
8. Protein gene product (PGP). 9.5 in diagnostic (neuro-) oncology. An immunomorphological study
9. Prostate cancer in a transgenic mouse
10. The rat probasin gene promoter directs hormonally and developmentally regulated expression of a heterologous gene specifically to the prostate in transgenic mice
11. Transgenic hepatocarcinogenesis in the rat
12. Extrapulmonary oat-cell carcinoma of the tongue: An electron-microscopic study
13. The taste bud and its innervation in the rat as studied by immunohistochemistry for PGP 9.5
14. Decrease of prostaglandin E2 and 5-bromo-2′-deoxyuridine labeling but not prostate tumor development by indomethacin treatment of rats given 3,2′-dimethyl-4-aminobiphenyl and testosterone propionate
15. T antigen is bound to a host protein in SV40-transformed cells
16. Characterization of a 54K dalton cellular SV40 tumor antigen present in SV40-transformed cells and uninfected embryonal carcinoma cells
17. Chemoprevention of rat prostate carcinogenesis by 9-cis-retinoic acid
18. Oat cell carcinoma of the tongue from an unknown primary
19. Effects of tamoxifen, an antiestrogen, on rat prostate carcinogenesis by 3,2′-dimethyl-4-aminobiphenyl and testosterone do not support an estrogen role in testosterone promotion
20. Polyoma small and middle T antigens and SV40 small T antigen form stable complexes with protein phosphatase 2A
21. Characterization of two cis-acting DNA elements involved in the androgen regulation of the probasin gene
22. Mouse models of prostate cancer
23. Progression of prostatic intraepithelial neoplasia to invasive carcinoma in C3(1)/SV40 large T antigen transgenic mice: Histopathological and molecular biological alterations
24. Effects of testosterone, dihydrotestosterone and estrogen on 3,2′-dimethyl-4-aminobiphenyl-induced rat prostate carcinogenesis
25. Experimental prostate carcinogenesis - Rodent models
26. A five-alpha reductase inhibitor or an antiandrogen prevents the progression of microscopic prostate carcinoma to macroscopic carcinoma in rats
27. Synaptophysin identified in metastases of neuroendocrine tumors by immunocytochemistry and immunoblotting