Protection of vascular wall function in insulin-resistant rats from copper oxidative stress

British Journal of Pharmacology

Volumn 133, Issue 4, 2001, Pages 477-484

  O'Brien, Sheila F ^a   Davidge, Sandra T ^a   Zhang, Yunlong ^a   Russell, James C ^a  

^a UNIVERSITY OF ALBERTA   (Canada)

Author keywords

Copper; Endothelium; Nitric oxide; Obesity; Smooth muscle

Indexed keywords

ACETYLCHOLINE; CATALASE; COPPER; NITRIC OXIDE; NITROPRUSSIDE SODIUM; NORADRENALIN; SUPEROXIDE DISMUTASE; ZINC;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTERY ENDOTHELIUM; ARTERY MUSCLE; ARTICLE; BLOOD VESSEL WALL; CONTROLLED STUDY; INSULIN RESISTANCE; MALE; MESENTERIC ARTERY; NONHUMAN; OBESITY; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT; SMOOTH MUSCLE RELAXATION;

EID: 0034956381     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0704095     Document Type: Article

References (34)

1. The retardation of vasculopathy induced by attenuation of insulin resistance in the corpulent JCR: LA-cp rat is reflected by decreased vascular smooth muscle cell proliferation in vivo
2. Increased proliferation of explanted vascular smooth muscle cells: A marker presaging atherogenesis
3. 2+-dependent retraction of vascular smooth muscle cells
4. 2+ mobilization in human pulmonary arterial cells
5. Hyperinsulinemia as an independent risk factor for ischemic heart disease
6. Recovery by ascorbate of impaired nitric oxide-dependent relaxation resulting from oxidative stress in rat aorta
7. The soluble guanylyl cyclase inhibitor 1H-[1,2,4]oxadiazolo[4,3,-3a]quinoxalin-1-one is a nonselective heme protein inhibitor of nitric oxide synthase and other cytochrome P-450 enzymes involved in nitric oxide donor bioactivation
8. Content of antioxidants, preformed lipid hydroperoxides, and cholesterol as predictors of the susceptibility of human LDL to metal ion-dependent and -independent oxidation
9. Regulation of the vascular extracellular superoxide dismutase by nitric oxide and exercise training
10. Copper stimulates proliferation of human endothelial cells under culture
11. Relationship of calcium, magnesium, zinc and copper concentrations in the arterial wall and serum in atherosclerosis obliterans and aneurysm
12. Copper enhances EDNO (endothelium-derived nitric oxide) activity by cultured human vascular cells
13. Investigation of oxidant stress and vasodepression to glyceryl trinitrate in the obese Zucker rat in vivo
14. Loss of endothelium-derived nitric oxide in rabbit aorta by oxidant stress: Restoration by superoxide dismutase mimetics
15. Nitric oxide: Physiology, pathophysiology, and pharmacology
16. Ceruloplasmin copper induces oxidant damage by a redox process utilizing cell-derived superoxide as a reductant
17. Insulin resistance and vascular wall function: Lessons from animal models
18. Vascular wall dysfunction in JCR: LA-cp rats: Effects of age and insulin resistance
19. Oxidative stress and insulin action: Is there a relationship?
20. Effect of copper on nitric oxide synthase and guanylyl cyclase activity in the rat isolated aorta
21. Pathophysiology of insulin resistance in human disease
22. Vasculopathy and insulin resistance in the JCR: LA-cp rat
23. Oxidant stress reduces insulin responsiveness in 3T3-L1 adipocytes
24. Myocardial and vascular lesions in the LA/N-corpulent rat
25. Inhibition of atherosclerosis and myocardial lesions in the JCR: LA-cp rat by β,β′tetramethyl-hexadecanedioic acid (MEDICA 16)
26. Development of insulin resistance in the JCR: LA-cp rat: Role of triacylglycerols and effects of MEDICA 16
27. Autoantibody against oxidised LDL and progression of carotid disease
28. Dietary copper in the physiology of the microcirculation
29. Endothelial cells prevent accumulation of lipid hydroperoxides in low-density lipoprotein
30. Obesity/insulin resistance is associated with endothelial dysfunction
31. Fatty streak formation in fat-fed mice expressing human copper-zinc superoxide dismutase
32. Differential sensitivity among nitric oxide donors toward ODQ-mediated inhibition of vascular relaxation
33. Impaired endothelium-dependent and independent dilatation of forearm resistance arteries in men with diet-treated non-insulin-dependent diabetes: Association with dyslipidaemia
34. Phenotype of the obese Koletsky (f) rat due to Tyr763Stop mutation in the extracellular domain of the leptin receptor