Possible existence of a novel receptor for uridine analogues in the central nervous system using two isomers, N3-(S)-(+)- and N3-(R)-(-)-α-hydroxy-β-phenethyluridines

Biological and Pharmaceutical Bulletin

Volumn 24, Issue 6, 2001, Pages 729-731

  Kimura, Toshiyuki ^a   Miki, Masaaki ^a   Ikeda, Michio ^a   Yonemoto, Sayaka ^a   Watanabe, Kazuhito ^a   Kondo, Shigemi ^b   Ho, Ing Kang ^c   Yamamoto, Ikuo ^a  

^a HOKURIKU UNIVERSITY   (Japan)

^b Central Research Laboratory of Nissui Pharmaceutical Co Ltd   (Japan)

^c UNIVERSITY OF MISSISSIPPI SCHOOL OF MEDICINE   (United States)

Author keywords

Central nervous system; Hypnotic; Isomer; N3 (S) (+) hydroxy phenethyluridine; N3 phenacyluridine; Uridine receptor

Indexed keywords

DRUG RECEPTOR; HYPNOTIC AGENT; LIGAND; N3 ALPHA HYDROXY BETA PHENETHYLURIDINE DERIVATIVE; UNCLASSIFIED DRUG; URIDINE DERIVATIVE;

ANIMAL TISSUE; ARTICLE; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; DRUG ACTIVITY; DRUG BINDING SITE; DRUG POTENCY; DRUG STRUCTURE; ISOMER; NONHUMAN; RACEMIC MIXTURE; SYNAPTIC MEMBRANE;

ANIMALS; BINDING SITES; CATTLE; CENTRAL NERVOUS SYSTEM; ISOMERISM; RECEPTORS, CELL SURFACE; URIDINE;

EID: 0034955175     PISSN: 09186158     EISSN: None     Source Type: Journal    
DOI: 10.1248/bpb.24.729     Document Type: Article

References (15)

1. Epilepsia