Nocodazole treatment of CV-1 cells enhances nuclear/perinuclear accumulation of lipid-DNA complexes and increases gene expression

Pharmaceutical Research

Volumn 18, Issue 2, 2001, Pages 246-249

  Lindberg, Jimmy ^a   Fernandez, Mary Ann M ^b   Ropp, J Dezz ^b,c   Hamm Alvarez, Sarah F ^a  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^b Urigen Pharmaceuticals Inc   (United States)

^c Ingenuity Systems Inc   (United States)

Author keywords

DNA; Liposome; Microtubule; Nocodazole; Taxol

Indexed keywords

DNA; LIPID; LIPOSOME; LUCIFERASE; NOCODAZOLE;

ANIMAL CELL; ARTICLE; CELL CULTURE; CELL LABELING; COMPLEX FORMATION; CONFOCAL MICROSCOPY; CONTROLLED STUDY; DRUG FORMULATION; DRUG MECHANISM; ENZYME ASSAY; GENE EXPRESSION; GENE TARGETING; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LIPID INTERACTION; REPORTER GENE;

ANIMALS; ANTINEOPLASTIC AGENTS; CELL NUCLEUS; CELLS, CULTURED; CERCOPITHECUS AETHIOPS; DNA; GENE EXPRESSION; GENES, REPORTER; LIPID METABOLISM; LUCIFERASES; NOCODAZOLE; PACLITAXEL; RHODAMINES; SUBCELLULAR FRACTIONS; TRANSFECTION;

EID: 0034954778     PISSN: 07248741     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1011001022570     Document Type: Article

References (8)

1. Nonviral gene therapy: Promises and challenges
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5. Paclitaxel and nocodazole differentially alter endocytosis in cultured cells
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7. Taxol induces bcl-2 phosphorylation and death of prostate cancer cells
8. Transient stimulation of the c-Jun-NH2-terminal kinase/activator protein 1 pathway and inhibition of extracellular signal-regulated kinase are early effects in paclitaxel-mediated apoptosis in human B lymphoblasts