Molecular characterization of thalassemia intermedia with homozygous Hb Malay and Hb Malay/HbE in Thai patients [1]

Haematologica

Volumn 86, Issue 6, 2001, Pages 657-658

  Fucharoen, S ^a   Sanchaisuriya, K ^a   Fucharoen, G ^a   Surapot, S ^a  

^a KHON KAEN UNIVERSITY   (Thailand)

Author keywords

Allele specific polymerase chain reaction (ASPCR); Hb Malay; Thalassemia intermedia

Indexed keywords

GAMMA GLOBIN; HEMOGLOBIN E; TAQ POLYMERASE;

ADULT; ALLELE; BLOOD TRANSFUSION; CASE REPORT; DIFFERENTIAL DIAGNOSIS; DNA DETERMINATION; ELECTROPHORESIS; FEMALE; GENE MUTATION; HAPLOTYPE; HOMOZYGOSITY; HUMAN; LABORATORY DIAGNOSIS; LETTER; MALE; POLYMERASE CHAIN REACTION; SEQUENCE ANALYSIS; THAILAND; THALASSEMIA;

ADULT; BETA-THALASSEMIA; DNA MUTATIONAL ANALYSIS; FEMALE; HEMOGLOBIN E; HEMOGLOBINS, ABNORMAL; HETEROZYGOTE; HOMOZYGOTE; HUMANS; MALE; THAILAND;

EID: 0034954295     PISSN: 03906078     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Letter

References (10)

1. Molecular characterization of β-globin gene mutations in Malay patients with Hb E-β-thalassaemia major
2. Molecular basis of β-thalassemia in Thailand: Analysis of β-globin gene mutations using the polymerase chain reaction
3. Abnormal processing of β-Malay globin RNA
4. Clinical, hematological and molecular features in Thais with β-Malay/β-thalassemia and β-Malay/HbE
5. Double heterozygosity of the β-Malay and a novel β-thalassemia gene in a Thai patient
6. β-thalassemia intermedia caused by compound heterozygosity for Hb Malay β codon 19 AAC→AGC; asn→Ser) and codons 41/42 (-CTTT) β(O)-thalassemia mutation
7. Generation and spread of globin mutations in populations: β-thalassemia in Asian countries
8. Gγ-globin gene in the Japanese HPFH: Implication of factor binding in elevated fetal globin expression