Effect of recombinant bactericidal/permeability-increasing protein on endotoxin translocation and lipopolysaccharide-binding protein/CD14 expression in rats after thermal injury

Critical Care Medicine

Volumn 29, Issue 7, 2001, Pages 1452-1459

  Fang, W H ^a   Yao, Y M ^a   Shi, Z G ^a   Yu, Y ^a   Wu, Y ^a   Lu, L R ^a   Sheng, Z Y ^a  

^a 304TH HOSPITAL   (China)

Author keywords

Bacterial translocation; Bactericidal permeability increasing protein; Burns; CD14; Endotoxin; Gene expression; Lipopolysaccharide; Lipopolysaccharide binding protein; Multiple organ failure; Rats; Tumor necrosis factor

Indexed keywords

ALBUMIN; CD14 ANTIGEN; ENDOTOXIN; LIPOPOLYSACCHARIDE BINDING PROTEIN; MESSENGER RNA; RECOMBINANT BACTERICIDAL PERMEABILITY INCREASING PROTEIN; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ARTICLE; BACTERIAL TRANSLOCATION; BURN; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DISEASE SEVERITY; DOWN REGULATION; GENE EXPRESSION; INTENSIVE CARE; MULTIPLE ORGAN FAILURE; NONHUMAN; PRIORITY JOURNAL; PROSPECTIVE STUDY; PROTEIN EXPRESSION; RANDOMIZED CONTROLLED TRIAL; RAT; THERMAL INJURY;

EID: 0034954223     PISSN: 00903493     EISSN: None     Source Type: Journal    
DOI: 10.1097/00003246-200107000-00025     Document Type: Article

References (38)

1. The inflammatory basis of trauma/shock associated multiple organ failure
2. Role of the gut in multiple organ failure: Bacterial translocation and permeability changes
3. Antiendotoxin strategies for the prevention and treatment of septic shock. New approaches and future directions
4. A second large controlled clinical study of E5, a monoclonal antibody to endotoxin: Results of a prospective multicenter, randomized, controlled trial
5. Another negative clinical trial of a new agent for the treatment of sepsis: Rethinking the process of developing adjuvant-treatment for serious infections
6. Transfection of CD14 in 70Z/3 cells dramatically enhances the sensitivity to complexes of lipopolysaccharide (LPS) and LPS binding protein
7. Elevated plasma neopterin level: Its relation to endotoxaemia and sepsis in patients with major burns
8. Endotoxin after gut ischemia/reperfusion causes irreversible lung injury
9. Sensitivity to endotoxin in rabbits is increased after hemorrhagic shock
10. Thermal injury induces macrophage hyperactivity through pertussis toxin-sensitive and -insensitive pathways
11. Isolation of a lipopolysaccharide-binding acute phase reactant from rabbit serum
12. CD14, a receptor for complexes of lipopolysaccharide (LPS) and LPS binding protein
13. LPS-binding protein and receptors
14. The level of lipopolysaccharide-binding protein is significantly increased in plasma in patients with the systemic inflammatory response syndrome
15. Increased soluble CD14 levels correlate with endotoxemia in critical patients with multiple organ failure
16. Crystal structure of human BPI and two bound phospholipids at 4.5 angstrom resolution
17. Treatment with recombinant bactericidal/permeability-increasing protein to prevent endotoxin-induced mortality in bile duct-ligated rats
18. 21) in baboon sepsis is related to its antibacterial, not antiendotoxin, properties
19. Inhibition of endotoxin-induced cytokine release and neutrophil activation in humans by use of recombinant bactericidal/permeability-increasing protein
20. Preliminary evaluation of recombinant amino-terminal fragment of human bactericidal/permeability-increasing protein in children with severe meningococcal sepsis
21. Pathogenesis of hemorrhage-induced bacteria/endotoxin translocation in rats: Effects of recombinant bactericidal/permeability-increasing protein
22. Role of gut-derived endotoxaemia and bacterial translocation in rats after thermal injury: Effects of selective decontamination of the digestive tract
23. Single-step method of RNA isolation by acid guanidinium thiocyanate-chloroform extraction
24. Molecular cloning, characterization, and tissue distribution of rat lipopolysaccharide binding protein
25. CD14 mediates endotoxin induction of nitric oxide synthase in cultured brain glial cells
26. Rat tumor necrosis factor-α: Transcription in rat Kupffer cells and in vitro posttranslational processing based on a PCR-derived cDNA
27. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
28. Estimation of diamine oxidase activity by o-dianisidine peroxidase coupling
29. The gut: The "motor" of multiple organ dysfunction syndrome?
30. Effects of recombinant bactericidal, permeability increasing protein on bacterial translocation and pulmonary neutrophil sequestration in burned mice
31. Increased circulating soluble CD14 is associated with high mortality in Gram-negative septic shock
32. Antibodies against CD14 protect primates from endotoxin-induced shock
33. Relationship between soluble CD14, lipopolysaccharide binding protein, and the alveolar inflammatory response in patients with acute respiratory distress syndrome
34. Distinct patterns of differentiation induced in the monocytic cell line Mono Mac 6
35. Expression of CD14 by hepatocytes: Upregulation by cytokines during endotoxemia
36. Pulmonary LPS-binding protein (LBP) upregulation following LPS-mediated injury
37. Lipopolysaccharide-binding protein and bactericidal/permeability-increasing factor during hemodialysis: Clinical determinants and role of different membranes
38. Changes in polymorphonuclear leukocyte surface and plasma bactericidal/permeability-increasing protein and plasma lipopolysaccharide binding protein during endotoxemia or sepsis