A double-blind randomized comparative trial: Eberconazole 1% cream versus clotrimazole 1% cream twice daily in Candida and dermatophyte skin infections

Mycoses

Volumn 44, Issue 5-6, 2001, Pages 173-180

  Palacio, Amalia Del ^a   Ortiz, F J ^a   Perez A ^a   Pazos, C ^a   Garau, M ^a   Font, E ^a  

^a HOSPITAL UNIVERSITARIO 12 DE OCTUBRE   (Spain)

Author keywords

Antimycotic chemotherapy; Clotrimazole; Cutaneous candidosis; Dermatophytosis; Eberconazole; Topical therapy

Indexed keywords

CLOTRIMAZOLE; EBERCONAZOLE;

ADULT; AGED; ARTICLE; CANDIDA; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CREAM; DERMATOMYCOSIS; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; PHASE 3 CLINICAL TRIAL; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; RELAPSE; SKIN MANIFESTATION; TOPICAL TREATMENT;

ADMINISTRATION, TOPICAL; ANTIFUNGAL AGENTS; ARTHRODERMATACEAE; CANDIDA; CANDIDIASIS; CLOTRIMAZOLE; CYCLOHEPTANES; DERMATOMYCOSES; DOUBLE-BLIND METHOD; EPIDERMOPHYTON; HUMANS; IMIDAZOLES; TREATMENT OUTCOME; TRICHOPHYTON;

CANDIDA;

EID: 0034952724     PISSN: 09337407     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1439-0507.2001.00632.x     Document Type: Article

References (26)

1. Stiller, M. J. (1993) Systemic drugs in the treatment of dermatophytoses. Int. J. Dermatol. 32, 16-21.
2. Hay, R. J. (1990) Antifungal drugs in dermatology. Semin. Dermatol. 4, 309-317.
3. Font, E., Freixes, J. & Julve, J. (1994) Perfil del nuevo antimicótico lópieo Eberconazol. Rev. Iberoam. Micol. 11, 58-59.
4. Tomás, J. M., Camprubi, S., Merino, S., et al. (1993) Inhibition of two imidazole antimycotics, eberconazole and clotrimazole, by different components of Candida albicans serotype B membrane protoplast. Int. J. Antimicrob. Agents. 3, 61-64.
5. del Palacio, A., Cuétara, S. & Rodríguez-Noriega, A. (1995) Topical treatment of tinea corporis and tiena cruris with eberconazole (WAS 2160) cream 1% and 2%: a phase II dose-finding pilot study. Mycoses 38, 317-324.
6. Fredriksson, T. (1974) Topical treatment of superficial mycoses with clotrimazcle. Postgrad. Med. J. 50 (Suppl. 1), 62-64.
7. Oberste-Lehn, H. (1974) Ideal properties of a modern antifungal agent - the therapy of mycoses with clotrimazole. Postgrad. Med. J. 50 (Suppl. 1), 51-53.
8. Clayton, M. Y. & Connor. B. L. (1974) Clinical trial of clotrimazolc in the treatment of superficial fungal infections. Postgrad. Med. J. 50 (Suppl. 1), 66-68.
9. Aal, H. A. & Moawad, M. K. (1973) Clinical experience with Canesten cream (Bay b 5097) against dermatophytes in Egypt. Mykosen 16, 369-371.
10. Lassus, S. & Forsstroem, S. A. (1984) A double-blind parallel study comparing suleonazole with econazole in the treatment of dermatophytosis. Mykosen 27, 592-598.
11. Cullen, S. I. (1984) A comparison of a new antifuugal agent, 1 percent econazole nitrate (spectazole) cream in the treatment of intertriginous candidosis. Curr. Therapeut. Res. 35, 606-609.
12. Fredriksson. T. (1983) Treatment of dermatomycoses with topical tioconazole and miconazole. Dermatologica 166 (Suppl. 1), 14-19.
13. Deichmann, B. (1985) Bifonazol versus Miconazol. Therapiewoche 35, 3591-3594.
14. Hernández Pérez, E. (1384) Bifonazolc cream: once-a-day application every second day in tinea cruris and tinea corporis. Dermatologica 169 (Suppl. 1), 93-97.
15. Kuokkanen. (1982) Topical tioconazole in dermatomycosis. Mykosen 25, 274-280.
16. Kashin, P., Phyfferoen, M. C. & Gibbs, D. L. (1985) A comparative study of once versus twice daily treatment of superficial dermatophyte and yeasts infections with tioconazole 1% cream. J. Int. Med. Res. 13, 88-95.
17. Bogaert, H., Cordero, C., Ollague, W., et al. (1986) Multicentre double-blind clinical trials of ciclopiroxolamine cream 1% in the treatment of tinea corporis and tinea cruris. J. Int. Med. Res. 14, 210-216.
18. del Palacio, A., López, S., Gimeno, C., et al. (1991) A randomized comparative study: amorolfine (cream 0.125%, 0.25% and 0.5%) in dermatomycoses. J. Dermatol. Treat. 1, 299-303.
19. del Palacio Hernanz, A., López Gómez, S. & Moreno Palancar, P. (1989) A clinical double-blind trial comparing amorolfine cream 0.5% (RO-14-4767) with bifonazole cream 1% in the treatment of dermatomycoses. Clin. Exp. Dermatol. 14, 141-144.
20. Evans, E. G. V. (1997) The clinical efficacy of terbinafine in the treatment of fungal infections of the skin. Rev. Contemp. Pharmacother. 8, 325-341.
21. Ryder, N. S. (1989) The mechanism of action of terbinafine. Clin. Exp. Dermatol. 14, 98-100.
22. Clayton, Y. M. (1989) In vitro activity of terbinafine. Clin. Exp. Dermatol. 14, 101-103.
23. Cauwenbergh, G. & de Doncker, P. (1987) The clinical use of itraeonazole in suoerficial and deep mycoses. In: Fromtling, R. A. (ed.) Recent Trends in the Discovery, Development and Evaluation of Antifungals Agents Barcelona: J. R. Prous Science, pp 273-284.
24. del Palacio Hernanz, A., López Gómez, S., González Lastra, F., et al. (1990) A comparative double-blind study of terbinafine (Lamisil) and griseofulvin in tinea corporis and tinea cruris. Clin. Exp. Dermatol. 15, 210-216.
25. López Gómez, S., del Palacio, A., Van Cutsem, J., et al. (1994) Itraconazole versus griseofulvin in the treatment of tinea capitis: a double-blind randomized study in children. Int. J. Dematol. 33, 743-747.
26. Brachman, P. S. (1990) Epidemiology of infectious disease. Principles and methods. In: Mandell, G. Gordon Douglas, R and Bennett, J. (eds) Principles and Practice of Infectious Disease. New York: Churchill Livingstone, pp. 147-154.