A novel MVMp-based vector system specifically designed to reduce the risk of replication-competent virus generation by homologous recombination

Gene Therapy

Volumn 8, Issue 12, 2001, Pages 921-929

  Dupont, F ^a   Karim, A ^a   Dumon, J C ^b   Mine, N ^a   Avalosse, B ^a,c  

^a JULES BORDET INSTITUTE   (Belgium)

^b PASTEUR INSTITUTE OF BRUSSELS   (Belgium)

^c UNIVERSITÉ LIBRE DE BRUXELLES   (Belgium)

Author keywords

Autonomous parvovirus; Cancer gene therapy; MVMp based vectors; Recombination; Replication competent virus

Indexed keywords

DRUG VEHICLE; VIRUS VECTOR;

ANIMAL CELL; ARTICLE; CANCER THERAPY; CELL LINE; CERCOPITHECIDAE; CONTAMINATION; CONTROLLED STUDY; DRUG DESIGN; GENE EXPRESSION; GENE SEQUENCE; GENE THERAPY; GENETIC CODE; GENETIC COMPLEMENTATION; GENETIC RECOMBINATION; GENETIC TRANSFECTION; GENOME; HELPER VIRUS; HUMAN; HUMAN CELL; IN VIVO STUDY; NEWBORN; NONHUMAN; PARVOVIRUS; PLASMID; PRIORITY JOURNAL; PROBABILITY; RISK ASSESSMENT; SEQUENCE HOMOLOGY; VIRUS CAPSID; VIRUS INFECTION; VIRUS REPLICATION; VIRUS VIRULENCE;

EID: 0034952069     PISSN: 09697128     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.gt.3301477     Document Type: Article

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