Tephrosia purpurea alleviates phorbol ester-induced tumor promotion response in murine skin

Pharmacological Research

Volumn 43, Issue 2, 2001, Pages 135-144

  Saleem, Mohammad ^a   Ahmed, Salah Uddin ^a   Alam, Aftab ^a   Sultana, Sarwat ^a  

^a HAMDARD UNIVERSITY   (India)

Author keywords

Chemoprevention; Oxidative stress; Phorbol ester; Tumor promotion

Indexed keywords

7,12 DIMETHYLBENZ[A]ANTHRACENE; ACETONE; ANTINEOPLASTIC AGENT; CATALASE; CROTON OIL; DNA; GLUTATHIONE; GLUTATHIONE REDUCTASE; GLUTATHIONE TRANSFERASE; ORNITHINE DECARBOXYLASE; PHORBOL 13 ACETATE 12 MYRISTATE; PLANT EXTRACT; TEPHROSIA PURPUREA EXTRACT; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER PREVENTION; CHEMICAL CARCINOGENESIS; CHEMOPROPHYLAXIS; CONTROLLED STUDY; DNA SYNTHESIS INHIBITION; DOSE RESPONSE; ENZYME INHIBITION; HISTOPATHOLOGY; MALE; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; SKIN CARCINOGENESIS; SKIN TUMOR; TUMOR PROMOTION;

EID: 0034950941     PISSN: 10436618     EISSN: None     Source Type: Journal    
DOI: 10.1006/phrs.2000.0711     Document Type: Article

References (40)

1. Inhibition of benzoyl peroxide mediated tumor promotion in 7, 12, dimethyl benz(a) antharcene initiated skin of sencar mice by antioxidants Nordihydroguairetic acid and diallyl sulfide
2. Inhibition of 4-(methylnitrosamine)-1 (3-pyridyl)-1-butanone carcinogenesis in mice by d-limonene and citrus fruit oils
3. Inhibition of carcinogenesis by naturally occuring and synthetic compounds
4. Inhibition of tumor promotion in Sencar mouse skin by ethanol extract of Zingiber officinale rhizome
5. Cancer chemopreventive and therapeutic activities of red ginseng
6. Inhibition of neoplasia by minor dietary constituents
7. Anti-tumorigenic effect of crude extract of Viola odorata on DMBA induced two-stage skin carcinogenesis in the Swiss albino mice
8. Antitumor promoting activities of lantadenes on mouse skin tumors and mouse hepatic tumors
9. Polyphenols as cancer chemopreventive agents
10. Cancer chemoprevention: Principles and prospects
11. Carcinogenesis in mouse skin
12. Mechanism involved in two-stage carcinogenesis in mouse skin
13. Mutagen-carcinogens in foods
14. Activity guided isolation of constituents of Tephrosia purpurea with the potential to induce the phase II enzyme, quinone reductase
15. Tephrosia purpurea ameliorate benzoyl peroxide induced cutaneous toxicity in mice: Diminution of oxidative stress
16. Oral anti-inflammatory and anti-ulcerogenic activities of a hydroalcoholic extract and partitioned fraction of Turnera ulmifora
17. Antimicrobial activity of aerial parts of Drossera pelitata smith on oral bacteria
18. Alteration of glutathione S-transferase, lipid peroxidation in mouse skin and extra cutaneous tissue after topical application of gasoline
19. Iron overload augements 7, 12, DMBA initiated and TPA promoted skin tumorigenesis
20. Enhanced malignant progression of mouse skin tumors by the free radical generator benzoyl peroxide
21. Bromobenzene induced liver necrosis: Protective role of glutathione and evidence for 3, 4, bromobenzene oxide as the hepatotoxic intermediate
22. GST: The first enzymatic step in mercapturic acid formation
23. Glutathione reductase level in rat brain
24. Catalase activity
25. Induction of the polyamine biosynthesis enzymes in mouse epidermis by tumor promoting agents
26. Attenuation of iron-nitrilotriacetate (Fe-NTA) mediated renal oxidative stress, toxicity and hyperproliferative response by the prophylactic treatment of rats with garlic oil
27. Sn 1, 2, diacylglycerols mimic the effects of TPA in vivo by inducing biochemical changes associated with tumor promotion in mouse epidermis
28. An improved diphenylamine method for the estimation of deoxyribonucleic acid
29. Protein measurement with folin phenol reagent
30. Free radicals, antioxidant enzymes and carcinogenesis
31. Chemoprevention of colon carcinogenesis by dietary curcumin a naturally occuring plant phenolic compound
32. Inhibition of 12-0-tetradecanoyl phorbal acetate caused tumor promotion in 7, 12, dimethyl benz(a) anthracene-initiated sincar mouse by a polyphenol fraction
33. Ornithine decarboxylase as a target for chemoprevention
34. Inhibition of 2(3) tert-4-hydroxyanisole and other antioxidants of epidermal ornithine decarboxylase activity induced by 12-0-tetra decanoyl phorbol-13-acetate
35. Phorbol ester induced alteration of protein kinase C catalytic properties occurs at the membrane level and is not reproduced by physiological stimuli
36. Further characterization of tumor promoter mediated activities of protein kinase C