A nuclear magnetic resonance study of the miconazole-β-cyclodextrin inclusion complex in an acidic medium: Determination of the structure and stability constants

S.T.P. Pharma Sciences

Volumn 11, Issue 3, 2001, Pages 235-238

  Piel, G ^a   Llabres, G ^a   Evrard, B ^a   Van Hees, T ^a   De Hassonville, S H ^a   Delattre, L ^a  

^a UNIVERSITY OF LIÈGE   (Belgium)

Author keywords

cyclodextrin; Inclusion complexes; Miconazole; NMR spectroscopy

Indexed keywords

CYCLODEXTRIN; MICONAZOLE;

ACIDITY; ARTICLE; CHIRALITY; DRUG SOLUBILITY; DRUG STABILITY; DRUG STRUCTURE; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY;

EID: 0034948824     PISSN: 11571489     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (10)

1. Improvement of dissolution properties and microbiological activity of miconazole and econazole by cyclodextrin complexation
2. Isolation and antimycotic effect of a genuine miconazole β-cyclodextrine complex
3. Formation and antimycotic effect of cyclodextrin inclusion complexes of econazole and miconazole
4. Preparation, characterization, and evaluation of miconazole-cyclodextrin complexes for improved oral and topical delivery
5. Development of a non-surfactant parenteral formulation of miconazole by the use of cyclodextrins
6. Proton nuclear magnetic resonance study of the inclusion complex of naproxen with β-cyclodextrin
7. The crystal and molecular structure of trans-tetrakis (miconazole) cobalt II nitrate
8. Gradient-tailored excitation for single-quantum NMR spectroscopy of aqueous solutions
9. NMR investigation of the interaction of (+) and (-) flurbiprofen with βCD
10. Comparison of the IV pharmacokinetics in sheep of miconazole-cyclodextrin solutions and a micellar solution