Immune-specific up-regulation of adseverin gene expression by 2,3,7,8-tetrachlorodibenzo-p-dioxin

Molecular Pharmacology

Volumn 60, Issue 1, 2001, Pages 135-142

  Svensson, Camilla ^a   Lundberg, Katarina ^a,b  

^a UPPSALA UNIVERSITY   (Sweden)

^b Department of Pharmaceutical Biosciences   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

2,3,7,8 TETRACHLORODIBENZO PARA DIOXIN; ACTIN BINDING PROTEIN; ADSEVERIN; AROMATIC HYDROCARBON RECEPTOR; CYTOCHROME P450 1A1; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CYTOSKELETON; DOSE TIME EFFECT RELATION; GENE EXPRESSION; IMMUNOTOXICITY; MOUSE; MOUSE STRAIN; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECEPTOR UPREGULATION; THYMOCYTE; THYMUS;

EID: 0034948612     PISSN: 0026895X     EISSN: None     Source Type: Journal    
DOI: 10.1124/mol.60.1.135     Document Type: Article

References (40)

1. Dose-response relationship of cytochrome P4501b1 MRNA induction by 2,3,7,8-tetrachlorodibenzo-p-dioxin in livers of C57BL/6J and DBA/2J mice
2. Differential developmentally regulated expression of gelsolin family members in the mouse
3. The cytoskeleton in lymphocyte signaling
4. Non-carcinogenic effects of TCDD in animals
5. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
6. + T cells: Compulsory cytoskeletal alterations for the triggering of an intracellular calcium response
7. Down-regulation of major histocompatibility complex Q1b gene expression by 2,3,7,8-tetrachlorodibenzo-p-dioxin
8. The immunological synapse and the actin cytoskeleton: Molecular hardware for T cell signaling
9. Ontogenic development of murine fetal thymocytes is accelerated by 3,3′,4,4′-tetrachlorobiphenyl
10. Aryl-hydrocarbon receptor-deficient mice are resistant to 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced toxicity
11. Prothymocyte activity is reduced by perinatal 2,3,7,8-tetrachlorodibenzo-p-dioxin exposure
12. A novel response to dioxin. Induction of ecto-ATPase gene expression
13. Evidence for direct action of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on thymic epithelium
14. The aryl hydrocarbon receptor complex
15. Hemopoietic progenitors in the murine fetal liver capable of rapidly generating T cells
16. Immunological effects of chlorinated dibenzo-p-dioxins
17. p27(Kip1) induction and inhibition of proliferation by the intracellular Ah receptor in developing thymus and hepatoma cells
18. Thymic stroma exposed to aryl hydrocarbon receptor-binding xenobiotics fails to support proliferation of early thymocytes but induces differentiation
19. Functions of gelsolin: Motility, signaling, apoptosis, cancer
20. Cleavage of structural proteins during the assembly of the head of bacteriophage T4
21. Differential display of eukaryotic messenger RNA by means of the polymerase chain reaction
22. The actin-binding proteins adseverin and gelsolin are both highly expressed but differentially localized in kidney and intestine
23. 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) induced suppression of the local immune response
24. 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) alters intrathymic T-cell development in mice
25. 2+-mediated endonuclease activation
26. The Ah receptor: Mediator of the toxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) and related compounds
27. Hemopoietic stem cell transplantation using mouse bone marrow and spleen cells fractionated by lectins
28. Murine adseverin (D5), a novel member of the gelsolin family, and murine adseverin are induced by interleukin-9 in T-helper lymphocytes
29. Chromaffin cell scinderin, a novel calcium-dependent actin filament-severing protein
30. 2+ and pH determine the interaction of chromaffin cell scinderin with phosphatidylserine and phosphatidylinositol 4,5,-biphosphate and its cellular distribution during nicotinic-receptor stimulation and protein kinase C activation
31. Cytoskeletal rearrangement during migration and activation of T lymphocytes
32. Early T lymphocyte progenitors
33. Purification and characterization of mouse hematopoietic stem cells
34. Overexpression of the anti-apoptotic oncogene, bcl-2, in the thymus does not prevent thymic atrophy induced by estradiol or 2,3,7, 8-tetrachlorodibenzo-p-dioxin
35. Thymic alterations induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin are strictly dependent on aryl hydrocarbon receptor activation in hemopoietic cells
36. Gelsolin modulates phospholipase C activity in vivo through phospholipid binding
37. Sustained signaling leading to T cell activation results from prolonged T cell receptor occupancy. Role of T cell actin cytoskeleton
38. Mechanistic aspects of dioxin action
39. + T-cell lineage fate
40. Gene transcription in differentiating immature T cell receptor(neg) thymocytes resembles antigen-activated mature T cells