Possible involvement of protein kinases and Smad2 signaling pathways on osteoclast differentiation enhanced by activin A

Journal of Cellular Physiology

Volumn 188, Issue 2, 2001, Pages 236-242

  Murase, Yoshiyuki ^a   Okahashi, Nobuo ^a   Koseki, Takeyoshi ^b   Itoh, Kanami ^b   Udagawa, Nobuyuki ^c   Hashimoto, Osamu ^d   Sugino, Hiromu ^e   Noguchi, Toshihiide ^e   Nishihara, Tatsuji ^e  

^a AICHI GAKUIN UNIVERSITY   (Japan)

^b NATIONAL INSTITUTE OF INFECTIOUS DISEASES   (Japan)

^c SHOWA UNIVERSITY   (Japan)

^d UNIVERSITY OF TOKUSHIMA   (Japan)

^e KYUSHU DENTAL COLLEGE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVIN A; BINDING PROTEIN; CALCITRIOL; FOLLISTATIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1ALPHA; MITOGEN ACTIVATED PROTEIN KINASE; OSTEOCLAST DIFFERENTIATION FACTOR; PROSTAGLANDIN E2; PROTEIN KINASE; PROTEIN P44; SMAD PROTEIN; SMAD2 PROTEIN; SYNAPTOPHYSIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL CULTURE; CELL DIFFERENTIATION; CONTROLLED STUDY; NONHUMAN; OSTEOBLAST; OSTEOCLAST; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

ACTIVIN RECEPTORS; ACTIVINS; ANIMALS; BONE MARROW CELLS; CARRIER PROTEINS; CELL DIFFERENTIATION; CELLS, CULTURED; DNA-BINDING PROTEINS; FEMALE; FOLLISTATIN; GENE EXPRESSION; GLYCOPROTEINS; GROWTH SUBSTANCES; INHIBINS; MAP KINASE SIGNALING SYSTEM; MEMBRANE GLYCOPROTEINS; MICE; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; MITOGEN-ACTIVATED PROTEIN KINASES; OSTEOCLASTS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; RANK LIGAND; RECEPTOR ACTIVATOR OF NUCLEAR FACTOR-KAPPA B; RECEPTORS, GROWTH FACTOR; RNA, MESSENGER; SMAD2 PROTEIN; TRANS-ACTIVATORS;

EID: 0034942922     PISSN: 00219541     EISSN: None     Source Type: Journal    
DOI: 10.1002/jcp.1113     Document Type: Article

References (31)

1. Proposed standard nomenclature for new tumor necrosis factor family members involved in the regulation of bone resorption
2. Activin A is an essential cofactor for osteoclast induction
3. Follistatin and activin in bone: Expression and localization during endochondral bone development
4. A novel role of follistatin, an activin-binding protein, in the inhibition of activin action in rat pituitary cells. Endocytotic degradation of activin and its acceleration by follistatin associated with cell-surface heparan sulfate
5. TGF-beta signalling from cell membrane to nucleus through SMAD proteins
6. Possible role of hepatpcyte growth factor/scatter factor and activin A produced by the target organ in liver metastasis
7. Localization of follistatin, an activin-binding protein, in bone tissues
8. Tumor necrosis factor α stimulates osteoclast differentiation by a mechanism independent of the RANKL-RANK interaction
9. Bone morphogenetic protein-2 enhances osteoclast formation mediated by interleukin-1α through upregulation of osteoclast differentiation factor and cyclooxygenase-2
10. Dual effect of activin A on cell growth in Balb/c 3T3 cells
11. Activated T cells regulate bone loss and joint destruction in adjuvant arthritis through osteoprotegerin ligand
12. Functions of newly identified members of the tumor necrosis factor receptor/ligand superfamilies in lymphocytes
13. Activins, inhibins, and follistatin: Further thoughts on a growing family of regulators
14. Inhibition of vascular endothelial cell growth by activin-A
15. Reciprocal role of ERK and NF-κB pathways in survival and activation of osteoclasts
16. Activin-binding protein from rat ovary is follistatin
17. Activin A induces apoptotic cell death
18. Induction of prostanoid, nitric oxide, and cytokine formation in rat bone marrow derived macrophages by activin A
19. The isolation of polypeptides with FSH suppressing activity from bovine follicular fluid which are structurally different to inhibin
20. Advances in bone biology: The osteoclast
21. Activin enhances osteoclast-like cell formation in vitro
22. Modulation of osteoclast differentiation
23. Role of 1α,25-dihydroxyvitamin D3 in osteoclast differentiation and function
24. Modulation of osteoclast differentiation and function by the new members of the tumor necrosis factor receptor and ligand families
25. Osteoclast differentiation factor mediates an essential signal for bone resorption induced by 1α, 25-dihydroxyvitamin D3, prostaglandin E2, or parathyroid hormone in the microenvironment of bone
26. Isolation and partial characterization of follistatin: A single-chain Mr 35,000 monomeric protein that inhibits the release of follicle-stimulating hormone
27. Activation of p38mapk, MKK3, and MKK4 by TNF-α in mouse bone marrow-derived macrophages
28. Regulation of cellular and system function by activin
29. Activin A induction of cell-cycle arrest involves modulation of cyclin D2 and p21CIP / WAF1 in plasmacytic cells
30. Convergence of transforming growth factor-β and vitamin D signaling pathways on SMAD transcriptional coactivators
31. Activins and activin receptors in cell growth