Quantitative analysis of the EGF receptor autocrine system reveals cryptic regulation of cell response by ligand capture

Journal of Cell Science

Volumn 114, Issue 12, 2001, Pages 2301-2313

  DeWitt, Ann E ^a   Dong, Jian Ying ^b   Wiley, H Steven ^c   Lauffenburger, Douglas A ^a,d  

^a Massachusetts Institute of Technology Cambridge   (United States)

^b BOSTON CHILDREN S HOSPITAL   (United States)

^c PACIFIC NORTHWEST NATIONAL LABORATORY   (United States)

^d MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

Autocrine; Computational model; EGF

Indexed keywords

CELL RECEPTOR; EPIDERMAL GROWTH FACTOR; EPIDERMAL GROWTH FACTOR RECEPTOR; EPIDERMAL GROWTH FACTOR RECEPTOR ANTIBODY; LIGAND; METALLOPROTEINASE INHIBITOR; MONOCLONAL ANTIBODY;

ANIMAL CELL; ARTICLE; AUTOCRINE EFFECT; BREAST EPITHELIUM; CELL PROLIFERATION; CONTROLLED STUDY; CULTURE MEDIUM; EPITHELIUM CELL; FIBROBLAST; HUMAN; HUMAN CELL; MOLECULAR DYNAMICS; MOUSE; NONHUMAN; PARAMETER; PATHOLOGY; PHYSIOLOGY; PRIORITY JOURNAL; QUANTITATIVE ASSAY; REGULATORY MECHANISM; SIGNAL TRANSDUCTION;

ANIMALS; ANTIBODIES; AUTOCRINE COMMUNICATION; BREAST; CELL DIVISION; ENZYME ACTIVATION; EPIDERMAL GROWTH FACTOR; EPITHELIAL CELLS; FIBROBLASTS; HUMANS; KINETICS; LIGANDS; MICE; MODELS, BIOLOGICAL; RECEPTOR, EPIDERMAL GROWTH FACTOR; TRANSFECTION;

EID: 0034942833     PISSN: 00219533     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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