Spiral ligament pathology: A major aspect of age-related cochlear degeneration in C57BL/6 mice

JARO - Journal of the Association for Research in Otolaryngology

Volumn 2, Issue 2, 2001, Pages 118-129

  Hequembourg, Stephanie ^a   Liberman, M Charles ^a,b  

^a MASSACHUSETTS EYE AND EAR INFIRMARY   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

Author keywords

Aging; Cochlea; Hearing; Histopathology

Indexed keywords

AGE; AGING; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUDITORY RESPONSE; BRAIN STEM; DEMYELINATION; HAIR CELL; HEARING LOSS; HISTOLOGY; INNER EAR DISEASE; MOUSE; MOUSE STRAIN; NERVE CELL NECROSIS; NONHUMAN; PRIORITY JOURNAL; SENSORY NERVE CELL; TISSUE DEGENERATION;

EID: 0034941877     PISSN: 15253961     EISSN: None     Source Type: Journal    
DOI: 10.1007/s101620010075     Document Type: Article

References (29)

1. Characteristics of stria vascularis melanocytes of viable dominant spotting (Wv/Wv) mouse mutants
2. Comparison of demyelination and neural degeneration in spiral and Scarpa's ganglion of C57BL/6 mice
3. Bioelectric correlates of kanamycin intoxication
4. Peripheral anatomy and physiology II
5. Morphology of inner hair cell stereocilia in C57/6J mice as studied by scanning electron microscopy
6. Genotypic differences in behavioral, physiological and anatomical expression of age-related hearing loss in the laboratory mouse
7. Age-related changes in the murine cochlear lateral wall
8. Membrane resistance in endolymphatic walls of the first turn of the guinea pig cochlea
9. Auditory-nerve activity in cats exposed to ototoxic drugs and high-intensity sounds
10. Gap junctions in the rat cochlea: Immunohistochemical and ultrastructural analysis
11. Age-related loss of auditory sensitivity in two mouse genotypes
12. Effects of selective inner hair cell loss on DPOAE and CAP in carboplatin-treated chinchillas
13. Acoustic trauma in cats, cochlear pathology and auditory-nerve activity
14. Altered cochlear fibrocytes in a mouse model of DFN3 nonsyndromic deafness
15. Lateral wall Na,K-ATPase and endocochlear potentials decline with age in quiet-reared gerbils
16. The effects offurosemide on the endocochlear potential and auditory-nerve fiber tuning curves in cats
17. Age-related changes in the C57BL/6J mouse cochlea. II. Ultrastructural findings
18. Expression patterns of ion transport enzymes in spiral ligament fibrocytes change in relation to strial atrophy in the aged gerbil cochlea
19. Differentiation of inner ear fibrocytes according to their ion transport related activities
20. The fine structure of spiral ligament cells relates to ion return to the stria and varies with place-frequency
21. Innervation of the organ of Cord of the cat
22. Factors inducing retrograde degeneration of the cochlear nerve
23. Quantitative measures of hair cell loss in CBA and C57BL/6 mice throughout their life spans
24. Another role for melanocytes: Their importance for normal stria vascularis development in the mammalian inner ear
25. Expression of EphA4 in developing ears of the mouse and guinea pig
26. Pattern of degeneration of the spiral ganglion cell and its processes in the C57BL/6J mouse
27. The BALB/c mouse as an animal model for progressive sensorineural hearing loss
28. Atrophy of the spiral ligament