Role of prostanoids and endothelins in the prevention of cyclosporine-induced nephrotoxicity

Prostaglandins Leukotrienes and Essential Fatty Acids

Volumn 64, Issue 4-5, 2001, Pages 231-239

  Darlametsos, I E ^a   Varonos, D D ^a  

^a Centre Franco Hellénique De Recherches Biomédicales Nikolaos Papanikolaou   (Greece)

Author keywords

[No Author keywords available]

Indexed keywords

6 OXOPROSTAGLANDIN F1 ALPHA; ANGIOTENSIN; ARGIPRESSIN; ATRIAL NATRIURETIC FACTOR; CYCLOSPORIN A; DIPEPTIDYL CARBOXYPEPTIDASE; ENDOTHELIN 1; ENDOTHELIN RECEPTOR; FISH OIL; GAMMA LINOLENIC ACID; GLYCEROL; HISTAMINE RECEPTOR; HYDROXYICOSATETRAENOIC ACID; KETANSERIN TARTRATE; NIFEDIPINE; NITRIC OXIDE; NORADRENALIN; OZAGREL; PHOSPHOLIPASE A2; PHOSPHOLIPASE C; PRIMROSE OIL; PROSTACYCLIN; PROSTAGLANDIN E2; PROSTAGLANDIN SYNTHASE; RENIN; THROMBOXANE A2; THROMBOXANE B2;

ARTICLE; DIET SUPPLEMENTATION; GLOMERULUS FILTRATION RATE; HUMAN; NEPHROTOXICITY; NONHUMAN; PRIORITY JOURNAL; PROTECTION;

EID: 0034941379     PISSN: 09523278     EISSN: None     Source Type: Journal    
DOI: 10.1054/plef.2001.0265     Document Type: Article

References (91)

1. Areas for further experimentation to elucidate the immunosuppressive activity of cyclosporine
2. The biochemistry of cyclosporin formation: A review
3. Nephrotoxicity of cyclosporine A in liver and kidney transplant patients
4. Cyclosporine nephrotoxicity
5. Hypertension in cyclosporine-treated renal transplant recipients is sodium dependent
6. Hypertension after renal transplantation
7. Renal hypoperfusion as the primary cause of cyclosporine-induced nephropathy
8. Effects of Nva2-cyclosporine on glomerular filtration rate and renal blood flow in the rat
9. Cyclosporine-associated renal injury
10. Effect of cyclospodne on renin-angiotensin system
11. Effect of cyclosporine-A on rat catecholamines
12. Selective enhancement of thromboxane in macrophages and kidneys in cyclosporine induced nephrotoxicity
13. Effect of ketanserine in cyclosorine-induced renal dysfunction in rats
14. Cyclosporine-induced synthesis of endothelin by cultured human endothelial cells
15. Effect of nifedipine in cyclosporine-induced nephrotoxicity in rats: Roles of the thromboxane and endothelin systems
16. Pathophysiology of cyclosporine nephrotoxicity: Role of eicosanoids
17. The relationship of urinary thromboxane excretion to CsA nephrotoxicity
18. Effects of chronic cyclosporme administration on renal blood flow and intrarenal flow disturbition
19. Morphology of cyclosporin nephropathy
20. Cyclosporine-induced acute renal failure dysfunction in the rat
21. Role of endothelin in cyclosporine-induced glomerular dysfunction
22. Cyclosporine, the renin-angiotensin-aldosterone system and renal adverse reactions
23. Effect of cyclosporin on blood pressure and renin-aldosterone axis in rats
24. Effects of cyclosporine on the renin-angiotensin-aldosterone system and potassium excretion in renal transplant recipients
25. Serial changes in blood pressure, renal function, endothelin and lipoprotein (a) during the first 9 days of cyclosporin therapy in males
26. Glomerular hemodynamics and hormonal participation on cyclosporine nephrotoxicity
27. Combined antagonism of endothelin A/B receptors links endothelin to vasoconstriction whereas angiotensin II effects fibrosis
28. 2 synthesis partially protected while inhibition of angiotensin II formation did not protect rats against acute renal failure induced with glycerol
29. Effect of cyclosporine administration on renal hemodynamics in conscious rats
30. Prolonged unilateral acute renal failure induced by intra-arterial norepinephrine infusion in dog
31. Adrenergic blockades in ischemic acute renal failure in the rat
32. The role of volume expansion of prostaglandins and catecholamines in the development of acute renal failure
33. Gamma linoleic acid
34. 2 and triacylglycerol lipase on the synthesis and release of monoenoic and bisenoic prostaglandins from isolated rat uterus
35. The enzymes in cycloxygenase and lipoxygenase pathways of arachidonic acid metabolism in human corpora lutea: Dependence on luteal phase, cellular and subcellular distribution
36. Regional differences in the formation and metabolism of prostaglandins in the rabbit kidney
37. 1
38. 2 on renal failure due to glycerol in saline loaded rats
39. 2 in glycerol-induced acute renal failure in rats
40. 2 attenuates ischemic acute renal failure in the rat
41. 1 infusion in patients with chronic renal disease
42. Alteration of mercuric chloride-induced autoimmune glomerulonephritis and acute renal failure in brown norway rats. Omega-6 Essential Fatty Acids
43. An enzyme isolated from arteries transforms prostaglandin endoperoxides to an unstable substance that inhibits platelet aggregation
44. Prostaglandin synthesis by rat glomerular mesangial cells in culture
45. Prostaglandin and thromboxane synthesis by rat glomerular epithelial cells
46. Is thromboxane a potent anti-natriuretic factor and is it involved in the development of acute renal failure?
47. 2 synthesis in rats?
48. 2 biosynthesis in lung, spleen or platelets
49. Cyclosporin suppression of endothelial prostacyclin generation
50. 2 formation in isolated glomeruli and papillae of rat kidneys
51. 2 deficiency
52. 2 in rats caused by cyclosporine
53. Alteration of cyclosporine (CsA)-induced nephrotoxicity by gamma linolenic acid (GLA) and eicosapentaenoic acid (EPA) in wistar rats
54. Effects of OKY-046 and nffedipine in cyclosporine-induced renal dysfunction in rats
55. Antihypertensive properties of ketanserin (R 41 468)
56. Thromboxane a new group of biologically active compounds derived from prostaglandin endoperoxidase
57. The platelet as a mediator of tissue damage in immune complex glomerulonephritis
58. Coagulation and renal disease
59. The localization of circulating immune complexes in experimental serum sickness
60. 2 analogue reduces nephrotoxicity of cyclosporine in rats
61. Modulation of experimental cyclosporin nephrotoxicity by inhibition of thromboxane synthesis
62. Effect of dietary fish oil on renal function and rejection in cyclosporin treated recipients of renal transplants
63. Effects of diet supplementation with fish oil on renal function and the course of early postoperative rejection in cyclosporin A treated renal transplant recipients
64. Effects of thromboxane synthase inhibition with CGS 13080 in human cyclosporin nephrotoxicity
65. Endothelins
66. Potent selective vasoconstrictor effects of endothelin in the pig kidney in vivo
67. Mechanisms of disease
68. A novel potent vasoconstrictor peptide produced by vascular endothelial cells
69. Endothelin synthesis by rabbit renal tubule cells
70. Production of endothelin-1 by rat cultured mesangial cells
71. Synthesis of vasoconstrictor peptide endothelin in kidney cells
72. Increased urinary excretion of endothelin-1 and its precursor, big endothelin-1, in rats chronically treated with cyclosporine
73. 2-induced acute renal failure
74. Potential contribution of endothelin to renal abnormalities in glycerol-induced acute renal failure in rats
75. Effect of nifedipine on cyclosporine-A induced nephrotoxicity, urinary endothelin excretion and renal endothelin receptor number
76. Direct visualization of effects of endothelin on the renal microvasculature
77. Maintenance of endothelin-induced renal arteriolar constriction in rats is cyclooxygenase dependent
78. Cyclosporine-induced synthesis of endothelin by cultured human endothelial cells
79. Endothelin receptor antagonism is protective in vivo acute cyclosporine toxicity
80. Pressor effects of circulating endothelin are limited by its removal in the pulmonary circulation and by the release of prostacyclin and endothelium-derived relaxing factor
81. Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor
82. Endothelin increases atrial natriuretic peptide production in cultured rat diencephalic neurons
83. Cardiovascular, renal and endocrine responses to intravenous endothelin in conscious dogs
84. Integrated cardiac, renal, and endocrine actions of endothelin
85. Effects of endothelin on hemodynamics, prostaglandins, blood coagulation and renal function
86. Endothelin and eicosanoid synthesis in cultured mesangial cells
87. Characterization of endothelin 1 receptor and signal transduction mechanisms in rat medullary interstitial cells
88. 2 in anesthetized dogs
89. Acute haemodynamic and renal effects of cyclosporin and indomethacin in man