Synthesis of diverse 4,5-dihydro-3(2H)-pyridazinones on Wang resin

Journal of Pharmacy and Pharmacology

Volumn 53, Issue 7, 2001, Pages 981-985

  Gouault, N ^a   Cupif, J F ^a   Picard, S ^a   Lecat, A ^a   David, M ^a  

^a Institute de Chimie de'Rennes   (France)

Author keywords

[No Author keywords available]

Indexed keywords

4,5 DIHYDRO 3(2H) PYRIDAZINONE DERIVATIVE; HETEROCYCLIC COMPOUND; HYDRAZINE DERIVATIVE; HYDRAZONE DERIVATIVE; RESIN; SUCCINIC SEMIALDEHYDE;

ARTICLE; CYCLIZATION; DRUG ISOLATION; DRUG SYNTHESIS; MOLECULAR LIBRARY; POLYMERIZATION; REACTION ANALYSIS; SOLID STATE; STRUCTURE ANALYSIS;

BUTYRIC ACIDS; HYDRAZINES; HYDRAZONES; PYRIDAZINES; RESINS, PLANT;

EID: 0034940147     PISSN: 00223573     EISSN: None     Source Type: Journal    
DOI: 10.1211/0022357011776225     Document Type: Article

References (8)

1. 4,5-Dihydro-6-[4-(1H-imidazol-1-yl)phenyl]-3(2H)-pyridazinones: Novel positive inotropic agents for the treatment of congestive heart failure
2. Synthesis of 6-aryl-5-amino-3(2H)-pyridazinones as potential platelet aggregation inhibitors
3. Solid-phase synthesis, antiviral activity and cytotoxicity of some functionalized lactones
4. γ-Methyl-substituted-γ-butyrolactones: Solid-phase synthesis employing a cyclization-cleavage strategy
5. Synthesis of functionalized γ- and δ-lactones via polymer-bound epoxides
6. Solid-phase synthesis of bicyclo[2,2,2]octane derivatives via tandem Mickael
7. A new technique in preparing 2,4-dinitro-phenyl-hydrazones. Use of diglyme as solvent
8. Synthesis and structure-activity relationships of 4,5-dihydro-6-[4-(1H-imidazol-1-yl)phenyl]-3(2H)-pyridazinones: A new class of positive inotropic agents