Biostability and pharmacokinetics of LJP 920, an octameric Gal (α1-3) Gal conjugate for the inhibition of xenotransplantation rejection

Journal of Pharmacy and Pharmacology

Volumn 53, Issue 7, 2001, Pages 999-1005

  Jia, L ^a   Linnik, M D ^a   Jack, R M ^a   Yu, L ^a  

^a CTRC Institute for Drug Development   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY CONJUGATE; CARBOHYDRATE DERIVATIVE; GALACTOSE; LJP 920; UNCLASSIFIED DRUG;

ANALYTIC METHOD; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIBODY PRODUCTION; AREA UNDER THE CURVE; ARTICLE; B LYMPHOCYTE; CATALYSIS; DOSE RESPONSE; DRUG BLOOD LEVEL; DRUG DEGRADATION; DRUG DISTRIBUTION; DRUG ELIMINATION; DRUG ERYTHROCYTE LEVEL; DRUG HALF LIFE; DRUG STABILITY; DRUG SYNTHESIS; FEMALE; GRAFT REJECTION; INHIBITION KINETICS; LIVER MICROSOME; MALE; MAXIMUM ALLOWABLE CONCENTRATION; MOUSE; MOUSE STRAIN; NONHUMAN; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; TISSUE DISTRIBUTION; URINARY EXCRETION; XENOTRANSPLANTATION;

ANIMALS; BIOTRANSFORMATION; DISACCHARIDES; FEMALE; GRAFT REJECTION; IMMUNOSUPPRESSIVE AGENTS; MALE; MICE; MICE, INBRED BALB C; MICROSOMES, LIVER; TISSUE DISTRIBUTION; TRANSPLANTATION, HETEROLOGOUS;

EID: 0034939091     PISSN: 00223573     EISSN: None     Source Type: Journal    
DOI: 10.1211/0022357011776243     Document Type: Article

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