Localization of 3-nitrotyrosine to rheumatoid and normal synovium

Arthritis and Rheumatism

Volumn 44, Issue 7, 2001, Pages 1534-1539

  Mapp, Paul I ^a   Klocke, Rainer ^a   Walsh, David A ^b   Chana, Jasvinder K ^c   Stevens, Clifford R ^a   Gallagher, Patrick J ^d   Blake, David R ^a  

^a UNIVERSITY OF BATH   (United Kingdom)

^b UNIVERSITY OF NOTTINGHAM   (United Kingdom)

^c QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

^d SOUTHAMPTON GENERAL HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

3 NITROTYROSINE; ALPHA ACTIN; AVIDIN; BIOTIN; CD68 ANTIGEN; MONOCLONAL ANTIBODY; NITRIC OXIDE SYNTHASE; NITROGEN; PEROXYNITRITE; POLYCLONAL ANTIBODY;

ADULT; AGED; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE ASSOCIATION; FEMALE; HUMAN; HUMAN TISSUE; IMMUNOCYTOCHEMISTRY; IMMUNOREACTIVITY; INFLAMMATION; MACROPHAGE; MALE; PRIORITY JOURNAL; RHEUMATOID ARTHRITIS; SYNOVIUM; VASCULAR SMOOTH MUSCLE; VASCULAR TISSUE;

EID: 0034939015     PISSN: 00043591     EISSN: None     Source Type: Journal    
DOI: 10.1002/1529-0131(200107)44:7<1534::aid-art276>3.0.co;2-%23     Document Type: Article

References (15)

1. Evidence for nitric oxide-mediated oxidative damage in chronic inflammation: Nitrotyrosine in serum and synovial fluid from rheumatoid patients
2. Extensive nitration of protein tyrosines in human atherosclerosis detected by immunohistochemistry
3. Increased concentrations of nitrite in synovial fluid and serum samples suggest increased nitric oxide synthesis in rheumatic diseases
4. The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis
5. Immunohistochemical methods to detect nitrotyrosine
6. What nitrates tyrosine? Is nitrotyrosine specific as a biomarker of peroxynitrite formation in vivo?
7. Immunolocalization of inducible nitric oxide synthase in synovium and cartilage in rheumatoid arthritis and osteoarthritis
8. Pathological implications of nitric oxide, superoxide and peroxynitrite formation
9. The potential role of peroxynitrite in the vascular contractile and cellular energetic failure in endotoxic shock
10. Prolonged alteration of vasoconstrictor and vasodilator responses in rat knee joints by adjuvant monoarthritis
11. Mechanism of carbon dioxide-catalyzed oxidation of tyrosine by peroxynitrite
12. Xanthine oxidoreductase catalyses the reduction of nitrates and nitrite to nitric oxide under hypoxic conditions
13. Generation of nitric oxide by a nitrite reductase activity of xanthine oxidase: A potential pathway for nitric oxide formation in the absence of nitric oxide synthase activity
14. Reduction of nitrite to nitric oxide catalyzed by xanthine oxidoreductase
15. Antibacterial properties of xanthine oxidase in human milk