Polyvinylpyrrolidone and croscarmellose sodium interactions in fluidized bed granulations and their corresponding tablets

Pharmazeutische Industrie

Volumn 63, Issue 6, 2001, Pages 630-638

  Laohavichien, A ^a   Olin, B D ^a   Sakr, A ^a  

^a UNIVERSITY OF CINCINNATI MEDICAL CENTER   (United States)

Author keywords

Croscarmellose sodium, interactions; Fluidized bed granulation; Polyvinylpyrrolidone, interactions; Tablets

Indexed keywords

CROSCARMELLOSE SODIUM; POVIDONE;

ARTICLE; CONCENTRATION RESPONSE; DRUG FORMULATION; DRUG MANUFACTURE; DRUG SOLUBILITY; FLUIDIZED BED; TABLET; TABLET DISINTEGRATION TIME; TABLET FRIABILITY; TABLET HARDNESS;

EID: 0034937259     PISSN: 0031711X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (21)

1. Batch production of pharmaceutical granulations in a fluidized bed, II: Effects of various binders and their concentrations on granulations and compressed tablets
2. Granulation in a fluidized bed, II: Effect of binder amount on the final granules
3. The effect of variations in concentration and type of binder on the physical characteristics of sulfadiazine tablets and granulations prepared by wet and fluidised-bed granulation method
4. Evaluation of binder activities on the physical properties and compression characteristics of granules prepared by two different modes
5. Mode of action of polyvinylpyrrolidone as a binder on fluidized bed granulation of lactose and starch granules
6. Granulation in a fluidized-bed: Effect of binders and their concentrations on granule growth and modeling the relationship between granule size and binder concentration
7. Effect of the addition mode of the binder on the disintegration and dissolution of paracetamol tablets
8. Effect of mode of incorporation of disintegrants on the characteristics of fluid-bed wet-granulated tablets
9. A study of the effect of disintegrant distribution ratio on tablet characteristics using a central composite design
10. Directly compressible acetaminophen compositions prepared by fluidized-bed granulation
11. Characterization of wet granulation process parameters using response surface methodology, part 1: Top-spray fluidized bed
12. An evaluation of selected tablet disintegrants
13. Effect of mode of croscarmellose sodium incorporation on tablet dissolution and friability
14. Evaluation of smecta as a tablet disintegrant and dissolution aid
15. Effect of formulation solubility and hygroscopicity on disintegrant efficiency in tablets prepared by wet granulation, in terms of dissolution
16. Effect of the mode of superdisintegrant incorporation on dissolution in wet granulated tablets
17. Effect of aging on the dissolution of wet granulated tablets containing super disintegrants
18. Improvement of dissolution of poorly soluble drugs by solid deposition on a super disintegrant. Part 2. Choice of super disintegrants and effect of granulation
19. Effect of binders on the physical standards and dissolution characteristics of ephedrine hydrochloride tablets
20. Effect of disintegrant distribution on the physical standards of compressed tablets
21. Effect of granule size and compression