Potentiation of analgesia and reversal of tolerance to morphine by calcium channel blockers

Indian Journal of Experimental Biology

Volumn 39, Issue 7, 2001, Pages 636-642

  Verma, V ^a   Mediratta, P K ^a   Sharma, K K ^a  

^a UNIVERSITY COLLEGE OF MEDICAL SCIENCES   (India)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM; DRUG DOSAGE; DRUG INTERACTIONS; DRUG PRODUCTS;

ANALGESICS;

BIOCHEMISTRY;

CALCIUM CHANNEL BLOCKING AGENT; DILTIAZEM; FLUNARIZINE; MORPHINE; NIMODIPINE; VERAPAMIL;

ANALGESIA; ANIMAL; ARTICLE; DRUG EFFECT; DRUG INTERACTION; DRUG TOLERANCE; FEMALE; MALE; MOUSE; PAIN THRESHOLD; PHYSIOLOGY;

ANALGESIA; ANIMALS; CALCIUM CHANNEL BLOCKERS; DILTIAZEM; DRUG INTERACTIONS; DRUG TOLERANCE; FEMALE; FLUNARIZINE; MALE; MICE; MORPHINE; NIMODIPINE; PAIN THRESHOLD; VERAPAMIL;

EID: 0034936067     PISSN: 00195189     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (27)

1. The role of excitotoxicity in neuro-degenerative disease: Implications for therapy
2. Modification of endorphin/enkephelin analgesia and stress-induced analgesia by divalent cations, a cation chelator and an ionophore
3. Significance of calcium ion in the morphine analgesia
4. Hyperalgesic effects of divalent cations and antinociceptive effects of calcium chelators in naive and morphine dependent animals
5. Opiates activation of potassium conductance inhibits calcium action potentials in rat coeruleus neurons
6. Potentiation of thermoregularoty and analgesic effect of morphine by calcium channel antagonists
7. Analgesic effects of several calcium channel Mockers in mice
8. Calcium channel antagonists increase morphine-induced analgesia and antagonise morphine tolerance
9. Nifedipine-morphine interaction: A further investigation on nociception and locomotor activity in mice
10. Flunarizine analgesia is mediated by mu-opioid receptors
11. Comparison of phasic and tonic pain in animals
12. Multiple types of neuronal calcium channels and their selective modulation
13. Modified formalin test: Characteristic biphasic pain response
14. A method for evaluation of analgesic activity using rats
15. Studies on a new 1,5 benzothiazepine derivatives (CRD 401). III. Effect of optical isomer of CRD 401 on smooth muscle and other pharmacological properties
16. Nimodipine's interactions with other drugs. II. Diazepam
17. Selective calcium entry blocking properties of nicardipine
18. The formalin test in mice: Dissociation between inflammatory and non-inflammatory pain
19. Pharmacological interaction of the calcium channel blockers verapamil and flunarizine with the opioid system
20. Calcium agonists and antagonists of the dihydropyridine type: Antinociceptive effects, interference with opiate-μ-receptor agonists and neuropharmacological actions in rodents
21. k-opioid receptors and analgesia
22. Opioid receptors modulate diverse types of calcium channels in the nucleus tractus solitarius of the rat
23. 2+ channels
24. Different types of calcium channels mediate central synaptic transmission
25. 2+ channels in supporting hippocampal synaptic transmission
26. μ-opposing actions of the k-opioid receptors