Kinetic analysis of enzyme systems with suicide substrate in the presence of a reversible, uncompetitive inhibitor

BioSystems

Volumn 61, Issue 1, 2001, Pages 5-14

  Moruno Davila M A ^a   Garrido del Solo, C ^a   Garcia Moreno M ^a   Garcia Canovas F ^b   Varon R ^a  

^a UNIVERSITY OF CASTILLA LA MANCHA   (Spain)

^b UNIVERSITY OF MURCIA   (Spain)

Author keywords

Enzyme kinetic; Inhibitor; Numerical integration; Suicide substrates; Transient phase

Indexed keywords

ENZYME; ENZYME INHIBITOR; SUICIDE SUBSTRATE;

ARTICLE; COMPUTER PROGRAM; ENZYME INACTIVATION; ENZYME KINETICS; ENZYME MECHANISM; KINETICS; MICHAELIS MENTEN KINETICS; SIMULATION;

EID: 0034935318     PISSN: 03032647     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0303-2647(01)00117-4     Document Type: Article

References (26)

1. On the kinetics of suicide substrates
2. Klassische Runge-Kutta Formeln vierter und niedrigerer Ordnung mit Scherittweiten-Kontrolle und ihre Anwendung auf Wärmeleitungs-probleme
3. Estudio cinético sobre la fase de transición de enzimas tipo Michaelis con inhibición lineal e hiperbólica
4. Métodos para discriminar entre mecanismos clásicos de inhibición basados en la cinética de su fase de transición
5. Use of a windows program for simulation of the progress curves of reactants and intermediates involved in enzyme-catalyzed reactions
6. A general progress curve method for the kinetic analysis of suicide enzyme inhibitors
7. Kinetics of suicide substrates. Steady-state treatments and computer-aided exact solutions
8. Transient-phase kinetics of enzyme inactivation induced by suicide substrates
9. Kinetic characterisation of dopamine as a suicide substrate of tyrosinase
10. Kinetic study in the transient phase of the suicide inactivation of frog epidermis tyrosinase
11. Kinetics of enzyme systems with unstable suicide substrates
12. Transient phase of enzyme reactions. Time course equations of the strict and the rapid equilibrium conditions and their computerized derivation
13. Kinetics of suicide substrates
14. Kinetics of suicide substrates. Practical procedure for determining parameters
15. Suicide substrates, mechanism-based enzyme inactivators: recent developments
16. Kinetics of suicide substrates
17. An alternative method for determining inhibition rate constants by following the substrate reaction