99mTc-HMPAO (Ceretec) is stored in and released from the granules of eosinophil granulocytes

British Journal of Haematology

Volumn 114, Issue 1, 2001, Pages 185-190

  Moberg, Lena ^a   Karawajczyk, Malgorzata ^a   Venge, Per ^a,b  

^a UPPSALA UNIVERSITY   (Sweden)

^b UPPSALA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

ECP; Eosinophil; Leucocyte scintigraphy; MPO; Neutrophil

Indexed keywords

EOSINOPHIL CATIONIC PROTEIN; HEXAMETHYLPROPYLENE AMINE OXIME TECHNETIUM TC 99M; MYELOPEROXIDASE;

ARTICLE; CELL ORGANELLE; CELL SECRETION; CELL SEPARATION; ELECTRON MICROSCOPY; EOSINOPHIL; HUMAN; HUMAN CELL; INFLAMMATION; ISOTOPE LABELING; LEUKOCYTE; NEUTROPHIL; PRIORITY JOURNAL; SCINTIGRAPHY; SECRETORY GRANULE; SUCROSE DENSITY GRADIENT CENTRIFUGATION;

BLOOD PROTEINS; EOSINOPHIL GRANULE PROTEINS; EOSINOPHILS; HUMANS; INFLAMMATION; ISOTOPE LABELING; NEUTROPHILS; ORGANELLES; PEROXIDASE; RIBONUCLEASES; SECRETORY VESICLES; TECHNETIUM TC 99M EXAMETAZIME; TIME FACTORS;

EID: 0034935028     PISSN: 00071048     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2141.2001.02889.x     Document Type: Article

References (15)

1. Increased fecal eosinophil cationic protein in inflammatory bowel disease
2. Quantitative assessment of intestinal eosinophils and mast cells in inflammatory bowel disease
3. Quantification of inflammatory mediators in stool samples of patients with inflammatory bowel disorders and controls
4. Ultrastructural identification of exocytosis of granules from human gut eosinophils in vivo
5. Elastase in different primary granules of the human neutrophil
6. Neutrophil and eosinophil involvement of the small bowel in patients with celiac disease and Crohn's disease. Studies on the secretion rate and immunohistochemical localization of the granulocyte granule constituents in jejunum
7. An improved immunomagnetic procedure for the isolation of highly purified human blood eosinophils
8. Increased eosinophil granule proteins in gut lavage fluid from patients with inflammatory bowel disease
9. Activation of eosinophils in the pathophysiology of ulcerative colitis
10. Clinical experience with 99m-Tc-hexamethylpropyleneamineoxime for labelling leucocytes and imaging inflammation
11. Autoradiography and density gradient separation of technetium- 99m-exametazime (HMPAO) labelled leucocytes reveals selectivity for eosinophils
12. Inflammation: Imaging with Tc-99m HMPAO-labeled leukocytes
13. Neutrophils and eosinophils
14. Mechanisms for eosinophil degranulation: Release of the eosinophil cationic protein