Maximizing the success rate of minimal model insulin sensitivity measurement in humans: The importance of basal glucose levels

Clinical Science

Volumn 101, Issue 1, 2001, Pages 1-9

  Godsland, I F ^a   Walton, C ^a  

^a IMPERIAL COLLEGE SCHOOL OF MEDICINE   (United Kingdom)

Author keywords

Insulin resistance measurement; Minimal model intravenous glucose tolerance test

Indexed keywords

GLUCOSE; INSULIN;

ARTICLE; CLINICAL ARTICLE; CLINICAL PROTOCOL; COMPUTER PROGRAM; CONTROLLED STUDY; FEMALE; GLUCOSE METABOLISM; HEART FAILURE; HUMAN; INSULIN METABOLISM; INSULIN SENSITIVITY; INTRAVENOUS GLUCOSE TOLERANCE TEST; ISCHEMIC HEART DISEASE; MALE; MEASUREMENT; POSTMENOPAUSE; PRIORITY JOURNAL;

ANALYSIS OF VARIANCE; BLOOD GLUCOSE; CARDIAC OUTPUT, LOW; COMPUTER SIMULATION; CORONARY DISEASE; FEMALE; GLUCOSE CLAMP TECHNIQUE; GLUCOSE TOLERANCE TEST; HUMANS; INSULIN RESISTANCE; MALE; MODELS, BIOLOGICAL; NORMAL DISTRIBUTION; REPRODUCIBILITY OF RESULTS; SOFTWARE;

EID: 0034931636     PISSN: 01435221     EISSN: None     Source Type: Journal    
DOI: 10.1042/CS20000250     Document Type: Article

References (24)

1. Quantitative estimation of insulin sensitivity
2. Application of the minimal model of glucose kinetics
3. Equivalence of the insulin sensitivity index derived by the minimal model method and the euglycaemic clamp
4. Reassessment of glucose effectiveness and insulin sensitivity from minimal model analysis: A theoretical evaluation of the single-compartment glucose distribution assumption
5. Assessment of insulin sensitivity with minimal model: Role of model assumptions
6. The insulin sensitivity index in non-diabetic man. Correlation between clamp-derived and IVGTT-derived values
7. Methodological issues in the application of the minimal model: Effects of glucose dose, basal glucose concentration, test duration and modelling constraint
8. Assessment of insulin sensitivity in man: A comparison of minimal model and euglycaemic clamp derived measures in health and heart failure
9. Minimal model analysis of intravenous glucose tolerance test-derived insulin sensitivity in diabetic subjects
10. A comparison between the minimal model and the glucose clamp in the assessment of insulin sensitivity across a spectrum of glucose tolerance
11. Reduced sample number for calculation of insulin sensitivity and glucose effectiveness from the minimal model
12. Reduced sampling protocols in estimation of insulin sensitivity and glucose effectiveness using the minimal model in NIDDM
13. Estimation of insulin sensitivity and glucose clearance from minimal model: New insights from labelled IVGTT
14. Reproducibility and comparability of insulin sensitivity indices measured by stable-label intravenous glucose tolerance test
15. Hepatic glucose production during the labelled IVGTT: Estimation by deconvolution with a new minimal model
16. Insulin resistance, secretion and metabolism in users of oral contraceptives
17. Insulin resistance, secretion and elimination in postmenopausal women receiving oral or transdermal hormone replacement therapy
18. Insulin resistance in chronic heart failure: Relation to severity and etiology of heart failure
19. Evaluation of four mathematical models of glucose and insulin dynamics with analysis of the effects of age and obesity
20. MINMOD: A computer program to calculate insulin sensitivity and pancreatic responsivity from the frequently sampled intravenous glucose tolerance test
21. Assessment of insulin sensitivity in vivo
22. Role of glucose and insulin resistance in development of type 2 diabetes mellitus: Results of a 25-year follow-up study
23. Acute postchallenge hyperinsulinemia predicts weight gain: A prospective study
24. Modified protocols improve insulin sensitivity estimation using the minimal model