Evaluation of a rapid western immunoblotting procedure for the diagnosis of bovine spongiform encephalopathy (BSE) in the UK

Journal of Comparative Pathology

Volumn 125, Issue 1, 2001, Pages 64-70

  Cooley, W A ^a   Clark, J K ^a   Ryder, S J ^a   Davis, L A ^a   Farrelly, S S J ^a   Stack, M J ^a  

^a VETERINARY LABORATORIES AGENCY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

GLYCOSYLATED PROTEIN; PRION PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BOVINE SPONGIFORM ENCEPHALOPATHY; CATTLE; COMPARATIVE STUDY; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; DIAGNOSTIC VALUE; DISEASE MARKER; ELECTRON MICROSCOPY; HISTOPATHOLOGY; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; LABORATORY DIAGNOSIS; NONHUMAN; PROTEIN ANALYSIS; SCRAPIE; SENSITIVITY AND SPECIFICITY; TISSUE CULTURE; UNITED KINGDOM;

EID: 0034930258     PISSN: 00219975     EISSN: None     Source Type: Journal    
DOI: 10.1053/jcpa.2001.0478     Document Type: Article

References (40)

1. Similar signature of the prion protein in natural sheep scrapie and bovine spongiform encephalopathy-linked diseases
2. Western blot mapping of disease-specific amyloid in various animal species and humans with transmissible spongiform encephalopathies using a high-yield purification method
3. Identification of a protein that purifies with the scrapie prion
4. Diagnostic reliability of clinical signs in cows with suspected bovine spongiform encephalopathy
5. Transmissions to mice indicate that 'new variant' CJD is caused by the BSE agent
6. Brussels seeks BSE diagnostic test to screen European cattle
7. Identification of scrapie prion protein specific mRNA in scrapie-infected and uninfected brain
8. Molecular analysis of prion strain variation and the aetiology of 'new variant' CJD
9. Comparison of scrapie-associated fibril detection and Western immunoblotting for the diagnosis of natural ovine scrapie
10. Targeted surveillance for bovine spongiform encephalopathy
11. Post-mortem immunodiagnosis of scrapie and bovine spongiform encephalopathy
12. Hydrated autoclave pre-treatment enhancement of prion protein immunoreactivity in formalin-fixed bovine spongiform encephalopathy-affected brain
13. The same prion strain causes vCJD and BSE
14. Fibrils from brains of cows with new cattle disease contain scrapie-associated protein
15. Assessment of Western immunoblotting for the confirmatory diagnosis of ovine scrapie and bovine spongiform encephalopathy (BSE)
16. Sc)-specific epitope defined by a monoclonal antibody
17. Efficiency of Western blotting for the specific immunodetection of proteinase K-resistant prion protein in BSE diagnosis in France
18. Infection-specific particle from the unconventional slow virus diseases
19. Abnormal fibrils from scrapie-infected brain
20. Scrapie-associated fibrils in Creutzfeldt-Jakob disease
21. Tests for BSE evaluated
22. A cellular gene encodes scrapie PrP 27-30 protein
23. Sc detection and its use as a rapid surveillance method for the diagnosis of bovine spongiform encephalopathy (BSE)
24. Bovine spongiform encephalopathy: Detection of fibrils in the central nervous system is not affected by autolysis
25. Bovine spongiform encephalopathy: Detection and quantification of fibrils, fibril protein (PrP) and vacuolation in brain
26. Scrapie surveillance in Great Britain: Results of an abattoir survey, 1997/98
27. The diagnosis of bovine spongiform encephalopathy and scrapie by the detection of fibrils and the abnormal protein isoform
28. Scrapie-associated fibril detection on decomposed and fixed ovine brain material
29. Immunohistochemical detection and localisation of prion protein in brain tissue of sheep with natural scrapie
30. Bovine spongiform encephalopathy: Diagnostic significance of vacuolar changes in the selected nuclei of the medulla oblongata
31. Preliminary observations on the pathogenesis of experimental bovine spongiform encephalopathy (BSE): An update
32. Recently described scrapie-like encephalopathies of animals: Case definitions
33. A novel progressive spongiform encephalopathy in cattle
34. Correlation between the results of a histopathological examination and the detection of abnormal brain fibrils in the diagnosis of bovine spongiform encehalopathy
35. Configurations and topographic distribution of PrP in the central nervous system in bovine spongiform encephalopathy: An immunohistochemical study
36. Bovine spongiform encephalopathy: A neuropathological perspective
37. Bovine spongiform encephalopathy: Aspects of the clinical picture and analyses of possible changes 1986-1990