An isobolographic analysis of the adrenergic modulation of diclofenac antinociception

Anesthesia and Analgesia

Volumn 93, Issue 2, 2001, Pages 430-435

  Miranda, Hugo F ^a,b   Sierralta, Fernando ^a   Pinardi, Gianni ^a  

^a UNIVERSITY OF CHILE   (Chile)

^b Neuro endocrine Laboratory   (Chile)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA 1 ADRENERGIC RECEPTOR; ALPHA 2 ADRENERGIC RECEPTOR; CLONIDINE; DESIPRAMINE; DICLOFENAC; PHENYLEPHRINE; PRAZOSIN; PROSTAGLANDIN SYNTHASE INHIBITOR; YOHIMBINE;

ADRENERGIC STIMULATION; ANIMAL EXPERIMENT; ANTINOCICEPTION; ARTICLE; CONDUCTANCE; ENZYME INHIBITION; MOUSE; NEUROMODULATION; NEUROTRANSMISSION; NONHUMAN; PRIORITY JOURNAL; RECEPTOR BINDING;

EID: 0034925262     PISSN: 00032999     EISSN: None     Source Type: Journal    
DOI: 10.1213/00000539-200108000-00039     Document Type: Article

References (25)

1. Central effect of the non-steroid antiinflammatory agents, indomethacin, ibuprofen and diclofenac, determined in C fibre-evoked activity in single neurons of the rat thalamus
2. Central, naloxone-reversible antinociception by diclofenac in the rat
3. Diclofenac evaluated in a human experimental model of central pain
4. Nonsteroidal antiinflammatory drug modulation of behavioral responses to intrathecal N-methyl-D-aspartate, but not to substance P and amino-methyl-isoxazole-propionic acid in the rat
5. Effects of the combined oral administration of NSAIDs and dextromethorphan on behavioral symptoms indicative of arthritic pain in rat in rat
6. Mechanism of diclofenac analgesia: Direct blockade of inflammatory sensitization
7. Central antinociceptive effects of non-steroidal anti-inflammatory drugs and paracetamol
8. Transmitters involved in antinociception in the spinal cord
9. The effects of intrathecally administered opioid and adrenergic agents on spinal function
10. Previous administration of indomethacin or naloxone did not influence ketorolac antinociception in mice
11. Intrathecal morphine in mice: A new technique
12. Statistical analysis of drug-drug and site-site interactions with isobolograms
13. Interactions in the antinociceptive effect of tramadol in mice: An isobolographic analysis
14. The role of descending noradrenergic and serotonergic pathways in the modulation of nociception: Focus on receptor multiplicity
15. Peripheral and spinal mechanisms of antinociception
16. Selective antagonism of the antinociceptive effect of intrathecally applied alpha adrenergic agonists by intrathecal prazosin and intrathecal yohimbine
17. Systemic injections of alpha-1 adrenergic agonists produce antinociception in the formalin test
18. The antinociceptive effects of morphine, desipramine and serotonin and their combinations after intrathecal injection in the rat
19. The role of descending noradrenergic systems in regulation of nociception: The effects of intrathecally administered alpha-adrenoceptor antagonists and clonidine
20. Antinociceptive effects of intrathecal administration of alpha adrenoceptor antagonists and clonidine in the formalin test in the mouse
21. Functional comparison of neurotransmitter receptor subtypes in mammalian central nervous system
22. Pain modulation by adrenergic agents and morphine as measured in three pain tests
23. Involvement of adrenergic, serotonergic and opioid mechanisms in tramadol-induced antinociception in mice
24. Isobolographic analysis of interactions between intravenous morphine, propacetamol and diclofenac in carrageenin-injected rats