The relaxation induced by S-nitroso-glutathione and S-nitroso-N-acetylcysteine in rat aorta is not related to nitric oxide production

Journal of Pharmacology and Experimental Therapeutics

Volumn 298, Issue 2, 2001, Pages 686-694

  Ceron, Patrícia I B ^a   Cremonez, Daniela C ^a   Bendhack, Lusiane M ^a   Tedesco, Antonio C ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

1H 1,2,4 OXADIAZOLO[4,3 A]QUINOXALIN 1 ONE; 4 AMINOPYRIDINE; ACETYLCYSTEINE DERIVATIVE; ADENOSINE TRIPHOSPHATE; APAMIN; CALCIUM DERIVATIVE; CHARYBDOTOXIN; GLIBENCLAMIDE; GUANYLATE CYCLASE INHIBITOR; N ACETYL S NITROSOCYSTEINE; NITRIC OXIDE; PHENYLEPHRINE; POTASSIUM CHANNEL BLOCKING AGENT; POTASSIUM CHLORIDE; RYANODINE; S NITROSOCYSTEINE; S NITROSOGLUTATHIONE; THAPSIGARGIN; THIOL DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; AORTA; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG POTENCY; ENDOTHELIUM CELL; GLUTATHIONE METABOLISM; MALE; MEMBRANE CONDUCTANCE; NONHUMAN; POTASSIUM TRANSPORT; PRIORITY JOURNAL; RAT; VASCULAR ENDOTHELIUM; VOLTAGE CLAMP;

ACETYLCYSTEINE; ANIMALS; AORTA, THORACIC; ENDOTHELIUM, VASCULAR; ENZYME INHIBITORS; GLUTATHIONE; HYDROGEN-ION CONCENTRATION; MALE; MUSCLE RELAXATION; MUSCLE, SMOOTH, VASCULAR; NITRIC OXIDE; NITROSO COMPOUNDS; OXADIAZOLES; PHENYLEPHRINE; POTASSIUM CHANNEL BLOCKERS; POTASSIUM CHLORIDE; QUINOXALINES; RATS; RATS, WISTAR; RYANODINE; S-NITROSOGLUTATHIONE; THAPSIGARGIN; VASOCONSTRICTOR AGENTS; VASODILATION;

EID: 0034922715     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (31)

1. Nitric oxide and cGMP cause vasorelaxation by activation of a charybdotoxin-sensitive K channel by cGMP-dependent protein kinase
2. 2+]i in isolated rat mesenteric artery vascular smooth muscle cells
3. Nitric oxide as an inhibitory non-adrenergic non-cholinergic neurotransmitter
4. Nitric oxide: A physiologic mediator of penile erection
5. Alterations of calcium uptake in renovascular hypertensive rat aorta: Functional assessment with thapsigargin
6. The biochemical pathways of nitric oxide formation from nitrovasodilators: Appropriate choice of exogenous NO donors and aspects of preparation and handling of aqueous NO solutions
7. Correlation between nitric oxide formation during degradation of organic nitrates and activation of guanylate cyclase
8. The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine
9. Glutamate, nitric oxide and cell-cell signalling in the nervous system
10. In vivo evidence that L-s-nitrosocysteine may exert its vasodilator effects by interaction with thiol residues in the vasculature
11. The soluble guanylyl cyclase inhibitor 1H-[1,2,4] oxadiazolo[4,3-a]quinoxalin-1-one (ODQ) inhibits relaxation of rabbit aortic rings induced by carbon monoxide, nitric oxide, and glyceryl trinitrate
12. Endothelium-derived relaxing factor produced and released from artery and vein is nitric oxide
13. Mechanism of vascular smooth muscle relaxation by organic nitrates, nitrites, nitroprusside and nitric oxide: Evidence for the involvement of S-nitrosothiols as active intermediates
14. +2 stores
15. Formation of nitric oxide from L-arginine in the central nervous system: A transduction mechanism for stimulation of the soluble guanylate cyclase
16. Spontaneous liberation of nitric oxide cannot account for in vitro vascular relaxation by S-nitrosothiols
17. Time-dependent increase in nitric oxide formation concurrent with vasodilation induced by sodium nitroprusside, 3-morpholinosydnonimine, and S-nitroso-n-acetylpenicillamine but not by glyceryl trinitrate
18. Biological activity of S-nitrosothiols: The role of nitric oxide
19. Nonendothelial-derived nitric oxide activates the ATP-sensitive K channel of vascular smooth muscle cells
20. Biosynthesis of nitric oxide from L-arginine: A pathway for the regulation of cell function and communication
21. Selective guanylyl cyclase inhibitor reverses nitric oxide-induced vasorelaxation
22. The effect of 1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one (ODQ) and charybdotoxin (CTX) on relaxations of isolated cerebral arteries to nitric oxide
23. Vascular endothelial cells synthesize nitric oxide from L-arginine
24. Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor
25. Cyclic GMP-dependent protein kinase phosphorylates phospholamban in isolated sarcoplasmic reticulum from cardiac and smooth muscle
26. Hyperpolarization and relaxation of arterial smooth muscle caused by nitric oxide derived from the endothelium
27. 2+ channels markedly diminishes nitric oxide- but not L-s-nitrosocysteine- or endothelium-dependent vasodilation in vivo
28. L- and D-δ-nitroso-β,βdimethylcysteine differentially increase cGMP in cultured vascular smooth muscle cells
29. S-Nitrosation and reactions of S-nitroso compounds
30. Ca channels antagonizes NO-induced relaxation in pulmonary artery